HitPredict

Interactor 1: TRPG (P00937)
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2 (AS) (EC 4.1.3.27) (Anthranilate synthase, glutamine amidotransferase component); Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (PRAI)]
Gene: TRP3

Interactor 2: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.666

Property	Details
Experiments	26217697, 25452130, 19536198, 23217712
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 484 Sc			1 642
+	Sc
		343260 TRPG_YEAST (1-484): 0: 536: 100.00		HSP72_YEAST (1-642): 0: 922: 96.26
+	Sc
		491083 GUAA_YEAST (1-474): 8.03e-145: 426: 15.64		HSP71_YEAST (1-642): 0: 925: 100.00
+	Hs
		503692 GUAA_HUMAN (10-439): 1.49e-115: 357: 18.14		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Hs
		503486 PYR1_HUMAN (12-286): 8.56e-75: 258: 17.36		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Sc
		424282 PYR1_YEAST (13-286): 1.15e-74: 258: 18.44		HSP73_YEAST (1-642): 0: 925: 79.05
+	Sc
		424297 PYR1_YEAST (13-286): 1.15e-74: 258: 18.44		HSP71_YEAST (1-642): 0: 925: 100.00
+	Sc
		424298 PYR1_YEAST (13-286): 1.15e-74: 258: 18.44		HSP72_YEAST (1-642): 0: 922: 96.26
+	Sc
		424252 CARA_YEAST (3-242): 3.39e-60: 204: 19.03		HSP71_YEAST (1-642): 0: 925: 100.00
+	Sc
		490939 ADCS_YEAST (13-234): 2.78e-53: 193: 32.54		HSP71_YEAST (1-642): 0: 925: 100.00
+	Sc
		493721 ADCS_YEAST (13-234): 2.78e-53: 193: 32.54		HSP72_YEAST (1-642): 0: 922: 96.26