HitPredict

Interactor 1: Q05BA5 (Q05BA5)
Nuclear receptor coactivator
Gene: Ncoa3

Interactor 2: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20362541
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DUF4927~Hormone_recep, Hormone_recep~SRC-1
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1403 Mm			1 433
+	Mm
		63103 A5D6Q2_MOUSE (51-1403): 1.62e-168: 542: 100.00		ERR2_MOUSE (1-433): 1.96e-167: 478: 100.00
+	Hs
		343289 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		ERR2_HUMAN (1-433): 2.09e-167: 478: 93.07
+	Mm
		1053223 Q05BA5_MOUSE (1-1403): 6.74e-180: 574: 100.00		HNF4G_MOUSE (93-429): 7.9e-110: 331: 28.78
+	Hs
		625858 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		RXRA_HUMAN (8-431): 9.94e-131: 386: 28.44
+	Mm
		63118 A5D6Q2_MOUSE (51-1403): 1.62e-168: 542: 100.00		HNF4G_MOUSE (93-429): 7.9e-110: 331: 28.78
+	Hs
		343262 HIF1A_HUMAN (19-773): 3.25e-116: 386: 13.59		ERR2_HUMAN (1-433): 2.09e-167: 478: 93.07
+	Hs
		522840 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		COT1_HUMAN (26-429): 8.81e-121: 359: 29.31
+	Hs
		533239 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		RARB_HUMAN (41-430): 2.3e-117: 352: 28.32
+	Hs
		543603 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		ERR1_HUMAN (15-431): 2.68e-116: 348: 55.79
+	Hs
		397349 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		ESR1_HUMAN (10-432): 8.31e-114: 347: 33.05
+	Hs
		520654 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		RARA_HUMAN (38-430): 3.62e-113: 341: 27.64
+	Hs
		834106 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		HNF4A_HUMAN (78-429): 3.93e-111: 336: 27.48
+	Hs
		1095520 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		NR1H3_HUMAN (12-432): 4.72e-108: 328: 23.82
+	Hs
		565543 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		RARG_HUMAN (34-430): 9.83e-108: 327: 28.01
+	Hs
		652611 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		NR4A1_HUMAN (18-429): 5.07e-105: 325: 29.50
+	Hs
		933969 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		NR1H2_HUMAN (21-432): 6.59e-106: 322: 20.40
+	Hs
		533370 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		THB_HUMAN (23-430): 3.28e-103: 316: 24.78
+	Hs
		1367723 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		ESR2_HUMAN (102-433): 1.14e-69: 231: 38.61
+	Hs
		404582 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		GCR_HUMAN (99-352): 1.27e-45: 170: 37.98
+	Hs
		442969 NCOA3_HUMAN (1-1403): 2.59e-151: 497: 80.32		PRGR_HUMAN (92-369): 3.25e-45: 169: 31.08