HitPredict

Interactor 1: S1PR4 (O95977)
Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6)
Gene: S1PR4

Interactor 2: RAI3 (Q8NFJ5)
Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)
Gene: GPRC5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004930 - G protein-coupled receptor activity GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 384 Hs			1 357
+	Hs
		1339280 S1PR3_HUMAN (21-335): 3.19e-74: 237: 41.59		RAI3_HUMAN (1-357): 5.46e-113: 334: 100.00
+	Hs
		867646 GPR12_HUMAN (55-336): 2.32e-70: 225: 25.34		RAI3_HUMAN (1-357): 5.46e-113: 334: 100.00
+	Hs
		638217 S1PR1_HUMAN (1-359): 5.74e-67: 218: 37.88		RAI3_HUMAN (1-357): 5.46e-113: 334: 100.00
+	Hs
		770851 OPRM_HUMAN (2-365): 7.57e-77: 244: 14.06		GRM1_HUMAN (6-290): 6.99e-82: 272: 15.67
+	Hs
		1438459 LPAR2_HUMAN (21-350): 2.87e-88: 272: 37.50		GPC5C_HUMAN (5-337): 6.78e-75: 239: 35.78
+	Rn
		720592 AA2AR_RAT (45-322): 1.87e-74: 238: 23.33		GRM5_RAT (6-342): 2.63e-81: 270: 13.80
+	Hs
		709243 AA2AR_HUMAN (42-356): 2.06e-71: 230: 21.53		GRM5_HUMAN (6-342): 6.47e-81: 269: 13.80
+	Hs
		458499 ADRB2_HUMAN (16-347): 4.74e-74: 237: 18.60		GPC5B_HUMAN (8-353): 1.12e-83: 261: 32.88
+	Mm
		723352 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		GRM2_MOUSE (6-280): 2.6e-86: 280: 18.62
+	Mm
		723369 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		GRM5_MOUSE (6-342): 4.37e-81: 270: 13.80
+	Mm
		723338 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		GRM1_MOUSE (6-290): 4.47e-80: 267: 15.33
+	Hs
		1366278 LPAR1_HUMAN (3-348): 6.43e-66: 215: 30.79		GPC5B_HUMAN (8-353): 1.12e-83: 261: 32.88
+	Hs
		1404959 S1PR3_HUMAN (21-335): 3.19e-74: 237: 41.59		GPC5C_HUMAN (5-337): 6.78e-75: 239: 35.78
+	Hs
		709283 AA2BR_HUMAN (51-322): 8.11e-69: 221: 21.62		GPC5C_HUMAN (5-337): 6.78e-75: 239: 35.78
+	Hs
		1366255 LPAR1_HUMAN (3-348): 6.43e-66: 215: 30.79		GPC5C_HUMAN (5-337): 6.78e-75: 239: 35.78
+	Mm
		723576 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		GABR1_MOUSE (6-350): 6.08e-62: 215: 14.62
+	Mm
		723460 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		MGLYR_MOUSE (8-286): 7.62e-58: 204: 11.79
+	Mm
		723428 SSR3_MOUSE (10-342): 1.7e-65: 215: 15.67		GABR2_MOUSE (29-318): 1.79e-57: 202: 14.29