Protein: RAI3
Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)

Gene: RAI3, GPRC5A
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q8NFJ5

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005730 - nucleolus
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007175 - negative regulation of epidermal growth factor-activated receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

564090

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.650

High

375746

RASK
GTPase KRas

2

7

High-throughput

0.584

High

978173

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

1153415

CD226
CD226 antigen

1

2

High-throughput

0.575

High

1339292

GPC5B
G-protein coupled receptor family C group 5 member B

1

16

High-throughput

0.575

High

1339290

ANLN
Anillin

2

0

High-throughput

0.559

High

900933

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.536

High

901407

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.536

High

1233366

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.536

High

1325425

SYNPO
Synaptopodin

1

2

High-throughput

0.536

High

337122

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.528

High

408998

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.515

High

292701

RENR
Renin receptor

1

0

High-throughput

0.513

High

772913

MYH9
Myosin-9

1

0

High-throughput

0.513

High

958312

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1160690

DREB
Drebrin

1

0

High-throughput

0.513

High

1339296

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

1339277

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.489

High

126707

RHOD
Rho-related GTP-binding protein RhoD

1

10

High-throughput

0.479

High

178339

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

189718

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

218502

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

374788

RASH
GTPase HRas

1

6

High-throughput

0.479

High

401170

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

466366

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

537548

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

556226

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

562244

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

581178

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

582888

EZRI
Ezrin

1

3

High-throughput

0.479

High

601378

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

901954

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

941813

ARL4C
ADP-ribosylation factor-like protein 4C

1

5

High-throughput

0.479

High

945048

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

953571

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

958797

ARF3
ADP-ribosylation factor 3

1

2

High-throughput

0.479

High

962286

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

976431

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

988539

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

1125163

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

3

High-throughput

0.479

High

1151787

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

1339274

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1339284

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

1

Small-scale

0.479

High

1339286

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.479

High

1339301

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

1339285

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1339293

ANFY1
Rabankyrin-5

1

0

High-throughput

0.458

High

211155

CTR4
Cationic amino acid transporter 4

1

2

High-throughput

0.445

High

351928

S1PR4
Sphingosine 1-phosphate receptor 4

1

18

High-throughput

0.445

High

638217

S1PR1
Sphingosine 1-phosphate receptor 1

1

14

High-throughput

0.445

High

704047

5HT1E
5-hydroxytryptamine receptor 1E

1

6

High-throughput

0.445

High

834997

S19A1
Reduced folate transporter

1

2

High-throughput

0.445

High

845080

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.445

High

867646

GPR12
G-protein coupled receptor 12

1

13

High-throughput

0.445

High

907099

CCR9
C-C chemokine receptor type 9

1

4

High-throughput

0.445

High

912698

CTR2
Cationic amino acid transporter 2

1

2

High-throughput

0.445

High

1048372

ACVR1
Activin receptor type-1

1

2

High-throughput

0.445

High

1234870

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.445

High

1251162

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.445

High

1251667

T184A
Transmembrane protein 184A

1

1

High-throughput

0.445

High

1339272

MOT10
Monocarboxylate transporter 10

1

4

High-throughput

0.445

High

1339273

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

1

High-throughput

0.445

High

1339280

S1PR3
Sphingosine 1-phosphate receptor 3

1

12

High-throughput

0.445

High

1339281

SC6A7
Sodium-dependent proline transporter

1

5

High-throughput

0.445

High

1339282

S46A2
Solute carrier family 46 member 2

1

2

High-throughput

0.445

High

1339283

S19A3
Thiamine transporter 2

1

2

High-throughput

0.445

High

1339289

SO1B3
Solute carrier organic anion transporter family member 1B3

1

1

High-throughput

0.445

High

1339291

S17A5
Sialin

1

1

High-throughput

0.445

High

1339294

RHCG
Ammonium transporter Rh type C

1

1

High-throughput

0.445

High

1339297

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

1

High-throughput

0.445

High

1339298

FZD10
Frizzled-10

1

1

High-throughput

0.445

High

1339299

S6A14
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

1

5

High-throughput

0.445

High

1339300

FLVC2
Choline/ethanolamine transporter FLVCR2

1

3

High-throughput

0.445

High

138231

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

High-throughput

0.437

High

157636

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.437

High

323495

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.437

High

331163

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

349166

LATS1
Serine/threonine-protein kinase LATS1

1

3

High-throughput

0.437

High

1035794

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.437

High

1140587

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

1227089

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1339295

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.437

High

291682

XRP2
Protein XRP2

1

0

High-throughput

0.426

High

388436

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

1339271

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.426

High

1339287

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.426

High

1339303

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.426

High

62146

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

1

High-throughput

0.407

High

1239016

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.407

High

1329281

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.407

High

1339276

BSCL2
Seipin

1

1

High-throughput

0.407

High

1339279

MF14A
Hippocampus abundant transcript 1 protein

1

3

High-throughput

0.407

High

1339302

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

248008

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

1289247

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1293078

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1314517

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1339288

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

1325871

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low

1339275

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1339278

TM169
Transmembrane protein 169

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025