Protein: GPC5B
G-protein coupled receptor family C group 5 member B (A-69G12.1) (Retinoic acid-induced gene 2 protein) (RAIG-2)

Gene: GPC5B, GPRC5B
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9NZH0

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0004930 - G protein-coupled receptor activity
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1153448

CD226
CD226 antigen

1

2

High-throughput

0.691

High

1446822

GPC5C
G-protein coupled receptor family C group 5 member C

1

16

High-throughput

0.691

High

878106

AGRE5
Adhesion G protein-coupled receptor E5

3

2

High-throughput

0.662

High

140465

SDCB1
Syntenin-1

2

18

High-throughput

0.628

High

622697

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

4

High-throughput

0.628

High

963472

STXB1
Syntaxin-binding protein 1

2

8

High-throughput

0.628

High

1212216

MPP7
MAGUK p55 subfamily member 7

2

3

High-throughput

0.628

High

1436649

IPPK
Inositol-pentakisphosphate 2-kinase

2

1

High-throughput

0.628

High

1366278

LPAR1
Lysophosphatidic acid receptor 1

2

13

High-throughput

0.611

High

1358032

TM171
Transmembrane protein 171

3

1

High-throughput

0.609

High

1453246

SEC63
Translocation protein SEC63 homolog

3

2

High-throughput

0.604

High

749292

CD70
CD70 antigen

2

0

High-throughput

0.602

High

1057588

ACHD
Acetylcholine receptor subunit delta

2

0

High-throughput

0.602

High

125790

STXB3
Syntaxin-binding protein 3

2

8

High-throughput

0.601

High

1087318

STX4
Syntaxin-4

2

3

High-throughput

0.601

High

1097908

STX5
Syntaxin-5

2

4

High-throughput

0.601

High

1339292

RAI3
Retinoic acid-induced protein 3

1

16

High-throughput

0.575

High

814877

CUX1
Homeobox protein cut-like 1

2

4

High-throughput

0.571

High

1351829

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

2

2

High-throughput

0.558

High

458499

ADRB2
Beta-2 adrenergic receptor

1

9

Small-scale

0.552

High

1275419

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

3

High-throughput

0.549

High

1315492

K2013
Uncharacterized protein KIAA2013

2

1

High-throughput

0.549

High

1329321

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

2

High-throughput

0.549

High

1435765

AT133
Polyamine-transporting ATPase 13A3

2

2

High-throughput

0.549

High

702861

5HT2C
5-hydroxytryptamine receptor 2C

1

8

High-throughput

0.541

High

1416866

TACAN
Transmembrane protein 120A

1

1

High-throughput

0.541

High

127732

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

4

High-throughput

0.536

High

144328

ACACB
Acetyl-CoA carboxylase 2

1

1

High-throughput

0.536

High

160343

GOSR2
Golgi SNAP receptor complex member 2

1

1

High-throughput

0.536

High

163364

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

4

High-throughput

0.536

High

178991

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.536

High

226232

STX6
Syntaxin-6

1

1

High-throughput

0.536

High

249903

STX10
Syntaxin-10

1

1

High-throughput

0.536

High

299402

FLOT1
Flotillin-1

1

1

High-throughput

0.536

High

444004

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.536

High

463247

YES
Tyrosine-protein kinase Yes

1

4

High-throughput

0.536

High

477477

CD63
CD63 antigen

1

4

High-throughput

0.536

High

522747

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

2

High-throughput

0.536

High

655021

ITA6
Integrin alpha-6

1

1

High-throughput

0.536

High

658786

JAK1
Tyrosine-protein kinase JAK1

1

6

High-throughput

0.536

High

690128

AVR2A
Activin receptor type-2A

1

2

High-throughput

0.536

High

720346

UFO
Tyrosine-protein kinase receptor UFO

1

6

High-throughput

0.536

High

787353

ACV1B
Activin receptor type-1B

1

2

High-throughput

0.536

High

870804

CXA8
Gap junction alpha-8 protein

1

6

High-throughput

0.536

High

1090374

EPS8
Epidermal growth factor receptor kinase substrate 8

1

7

High-throughput

0.536

High

1091583

DLG1
Disks large homolog 1

1

3

High-throughput

0.536

High

1102767

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

2

High-throughput

0.536

High

1105253

S39A6
Zinc transporter ZIP6

1

2

High-throughput

0.536

High

1105880

TMED1
Transmembrane emp24 domain-containing protein 1

1

3

High-throughput

0.536

High

1133238

STAR3
StAR-related lipid transfer protein 3

1

1

High-throughput

0.536

High

1206165

TGO1
Transport and Golgi organization protein 1 homolog

1

4

High-throughput

0.536

High

1217571

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

5

High-throughput

0.536

High

1278328

LRP10
Low-density lipoprotein receptor-related protein 10

1

1

High-throughput

0.536

High

1290498

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

2

High-throughput

0.536

High

1326928

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.536

High

1358386

SCFD1
Sec1 family domain-containing protein 1

1

8

High-throughput

0.536

High

1383310

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

1

High-throughput

0.536

High

1394685

KIRR1
Kin of IRRE-like protein 1

1

1

High-throughput

0.536

High

1405310

PKP4
Plakophilin-4

1

3

High-throughput

0.536

High

1406216

OSMR
Oncostatin-M-specific receptor subunit beta

1

3

High-throughput

0.536

High

1407310

CML1
Chemerin-like receptor 1

1

5

High-throughput

0.536

High

1408347

PKP2
Plakophilin-2

1

3

High-throughput

0.536

High

1445835

ABCB6
ATP-binding cassette sub-family B member 6

1

1

High-throughput

0.536

High

1453244

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

1453247

AGRE2
Adhesion G protein-coupled receptor E2

1

2

High-throughput

0.536

High

1413824

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.518

High

573701

ENPL
Endoplasmin

1

2

High-throughput

0.515

High

212612

GPAA1
GPI-anchor transamidase component GPAA1

1

0

High-throughput

0.513

High

502573

H2A1
Histone H2A type 1

1

0

High-throughput

0.513

High

933067

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.513

High

1154771

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1245139

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

1280669

PKHH3
Pleckstrin homology domain-containing family H member 3

1

0

High-throughput

0.513

High

1406730

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

1451905

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

1453245

KLH13
Kelch-like protein 13

1

0

High-throughput

0.513

High

1453250

MYRF
Myelin regulatory factor

1

0

High-throughput

0.513

High

1399552

MIA2
Melanoma inhibitory activity protein 2

2

7

High-throughput

0.504

High

1402203

PIGS
GPI-anchor transamidase component PIGS

1

1

High-throughput

0.489

High

1432212

SPNS1
Protein spinster homolog 1

1

2

High-throughput

0.489

High

1439468

SEC12
Guanine nucleotide-exchange factor SEC12

1

2

High-throughput

0.489

High

1453249

B3GT5
Beta-1,3-galactosyltransferase 5

1

2

High-throughput

0.489

High

1407485

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.480

High

376029

RASK
GTPase KRas

1

6

High-throughput

0.479

High

1197727

MIDN
Midnolin

1

0

High-throughput

0.458

High

141956

PODXL
Podocalyxin

1

1

High-throughput

0.445

High

484232

PGFRB
Platelet-derived growth factor receptor beta

1

4

High-throughput

0.445

High

604244

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.445

High

641984

CD9
CD9 antigen

1

4

High-throughput

0.445

High

1119463

CASP
Protein CASP

1

6

High-throughput

0.445

High

1120651

DAG1
Dystroglycan 1

1

1

High-throughput

0.445

High

1144677

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

2

High-throughput

0.445

High

1154513

STXB2
Syntaxin-binding protein 2

1

8

High-throughput

0.445

High

1212313

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.445

High

106754

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

336276

BRI3
Membrane protein BRI3

1

0

High-throughput

0.426

High

536298

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.426

High

633435

ANPRB
Atrial natriuretic peptide receptor 2

1

0

High-throughput

0.426

High

753850

MRP1
Multidrug resistance-associated protein 1

1

0

High-throughput

0.426

High

890064

PSN1
Presenilin-1

1

0

High-throughput

0.426

High

1326575

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.426

High

1416627

STRA6
Receptor for retinol uptake STRA6

1

0

High-throughput

0.426

High

1449979

T106B
Transmembrane protein 106B

1

0

High-throughput

0.426

High

1453248

PCDGK
Protocadherin gamma-C3

1

0

High-throughput

0.426

High

1453251

PCDBE
Protocadherin beta-14

1

0

High-throughput

0.426

High

136558

GOLI4
Golgi integral membrane protein 4

1

3

High-throughput

0.407

High

946208

MLF1
Myeloid leukemia factor 1

2

0

High-throughput

0.313

High

1211213

ODR4
Protein odr-4 homolog

2

0

High-throughput

0.313

High

1450052

UFSP2
Ufm1-specific protease 2

2

0

High-throughput

0.313

High

1234753

CK071
Uncharacterized protein C11orf71

1

0

High-throughput

0.282

High

71257

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

1200378

KCP3
Keratinocyte-associated protein 3

1

0

High-throughput

0.279

Low

1210014

TM201
Transmembrane protein 201

1

0

High-throughput

0.279

Low

1229933

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

1238259

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1273292

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

1357339

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

1361372

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1388814

YIPF6
Protein YIPF6

1

0

High-throughput

0.279

Low

665736

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.232

Low

923675

RCAN1
Calcipressin-1

1

0

High-throughput

0.232

Low

1449024

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025