Protein: GPC5C
G-protein coupled receptor family C group 5 member C (Retinoic acid-induced gene 3 protein) (RAIG-3)

Gene: GPC5C, GPRC5C
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q9NQ84

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0005929 - cilium
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0030295 - protein kinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446822

GPC5B
G-protein coupled receptor family C group 5 member B

1

16

High-throughput

0.691

High

835398

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

5

High-throughput

0.662

High

1358025

TM171
Transmembrane protein 171

4

1

High-throughput

0.630

High

251477

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

2

1

High-throughput

0.628

High

320507

TM63A
Mechanosensitive cation channel TMEM63A

2

1

High-throughput

0.628

High

622684

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

4

High-throughput

0.628

High

669254

NK1R
Substance-P receptor

2

3

High-throughput

0.628

High

702851

5HT2C
5-hydroxytryptamine receptor 2C

2

8

High-throughput

0.628

High

719665

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

2

1

High-throughput

0.628

High

1280995

PXK
PX domain-containing protein kinase-like protein

2

6

High-throughput

0.628

High

1355934

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

1

High-throughput

0.628

High

1433356

GOLP3
Golgi phosphoprotein 3

2

1

High-throughput

0.628

High

976584

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.611

High

1242946

S39A4
Zinc transporter ZIP4

2

2

High-throughput

0.611

High

1366255

LPAR1
Lysophosphatidic acid receptor 1

2

13

High-throughput

0.611

High

219376

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.602

High

1187223

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

1350082

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

1446827

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

2

0

High-throughput

0.602

High

722632

CTR1
High affinity cationic amino acid transporter 1

2

2

High-throughput

0.601

High

1429291

S22A4
Solute carrier family 22 member 4

2

0

High-throughput

0.576

High

1446831

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.576

High

1400460

BTBD9
BTB/POZ domain-containing protein 9

2

4

High-throughput

0.574

High

1433343

GLP3L
Golgi phosphoprotein 3-like

2

1

High-throughput

0.574

High

1436643

IPPK
Inositol-pentakisphosphate 2-kinase

2

1

High-throughput

0.574

High

397011

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1315488

K2013
Uncharacterized protein KIAA2013

2

1

High-throughput

0.549

High

1391515

BSCL2
Seipin

2

1

High-throughput

0.549

High

166053

FFAR1
Free fatty acid receptor 1

1

4

High-throughput

0.536

High

178989

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.536

High

182789

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

210425

MTLR
Motilin receptor

1

5

High-throughput

0.536

High

349584

TSN15
Tetraspanin-15

1

5

High-throughput

0.536

High

640473

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

6

High-throughput

0.536

High

669073

FPR2
N-formyl peptide receptor 2

1

6

High-throughput

0.536

High

669289

PTAFR
Platelet-activating factor receptor

1

4

High-throughput

0.536

High

701436

5HT1B
5-hydroxytryptamine receptor 1B

1

7

High-throughput

0.536

High

709283

AA2BR
Adenosine receptor A2b

1

10

High-throughput

0.536

High

820588

GPV
Platelet glycoprotein V

1

3

High-throughput

0.536

High

868022

GLR
Glucagon receptor

1

6

High-throughput

0.536

High

868317

P2RY1
P2Y purinoceptor 1

1

4

High-throughput

0.536

High

870793

CXA8
Gap junction alpha-8 protein

1

6

High-throughput

0.536

High

878100

AGRE5
Adhesion G protein-coupled receptor E5

1

2

High-throughput

0.536

High

922841

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

1

High-throughput

0.536

High

1251689

T184A
Transmembrane protein 184A

1

1

High-throughput

0.536

High

1432422

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1438459

LPAR2
Lysophosphatidic acid receptor 2

1

13

High-throughput

0.536

High

1438761

GPR35
G-protein coupled receptor 35

1

4

High-throughput

0.536

High

1446820

GP173
Probable G-protein coupled receptor 173

1

9

High-throughput

0.536

High

1446826

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.536

High

1446833

GPR45
Probable G-protein coupled receptor 45

1

15

High-throughput

0.536

High

1446834

CXA3
Gap junction alpha-3 protein

1

6

High-throughput

0.536

High

165828

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.513

High

226373

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

380489

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.513

High

749403

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.513

High

1055144

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

0

High-throughput

0.513

High

1139034

SNX17
Sorting nexin-17

1

0

High-throughput

0.513

High

1168753

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1399621

OPALI
Opalin

1

0

High-throughput

0.513

High

1402494

SERC2
Serine incorporator 2

1

0

High-throughput

0.513

High

1446823

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

0

High-throughput

0.513

High

1446829

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

1239055

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.489

High

1412313

TMM79
Transmembrane protein 79

1

1

High-throughput

0.489

High

1446832

TBL2
Transducin beta-like protein 2

1

2

High-throughput

0.489

High

1365985

APBP2
Amyloid protein-binding protein 2

1

1

High-throughput

0.481

High

178409

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

189865

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

375984

RASK
GTPase KRas

1

7

High-throughput

0.479

High

537958

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

560531

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

562423

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

601460

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

630987

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

715796

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

956508

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.479

High

975266

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

1015821

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

1031554

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.479

High

1233509

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1271006

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.479

High

1367358

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1446830

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

1249237

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1446821

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.458

High

256165

S19A2
Thiamine transporter 1

1

2

High-throughput

0.445

High

604229

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.445

High

870319

S6A12
Sodium- and chloride-dependent betaine transporter

1

5

High-throughput

0.445

High

934288

BI1
Bax inhibitor 1

1

3

High-throughput

0.445

High

1093587

TRDN
Triadin

1

2

High-throughput

0.445

High

1139581

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.445

High

1234970

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.445

High

1404959

S1PR3
Sphingosine 1-phosphate receptor 3

1

12

High-throughput

0.445

High

1446828

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

2

High-throughput

0.445

High

827266

ARL1
ADP-ribosylation factor-like protein 1

1

4

High-throughput

0.437

High

366503

UROK
Urokinase-type plasminogen activator

1

0

High-throughput

0.426

High

1236336

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1313851

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.426

High

1402379

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.426

High

1348333

GOGA5
Golgin subfamily A member 5

1

6

High-throughput

0.407

High

1399549

MIA2
Melanoma inhibitory activity protein 2

1

7

High-throughput

0.407

High

1323888

SYNE4
Nesprin-4

3

0

High-throughput

0.347

High

1104767

NNTM
NAD(P) transhydrogenase, mitochondrial

3

0

High-throughput

0.345

High

884482

PCY1A
Choline-phosphate cytidylyltransferase A

2

0

High-throughput

0.328

High

1123135

FHL2
Four and a half LIM domains protein 2

2

0

High-throughput

0.328

High

1437617

NJMU
Protein Njmu-R1

2

0

High-throughput

0.328

High

1446825

FA8A1
Protein FAM8A1

2

0

High-throughput

0.328

High

49820

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1032137

FMO1
Flavin-containing monooxygenase 1

1

0

High-throughput

0.279

Low

1245926

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1248543

LCTL
Lactase-like protein

1

0

High-throughput

0.279

Low

1408143

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.279

Low

1432847

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

1446818

CP26B
Cytochrome P450 26B1

1

0

High-throughput

0.279

Low

350418

ABHGA
Phosphatidylserine lipase ABHD16A

1

0

Small-scale

0.265

Low

1446819

ZN277
Zinc finger protein 277

1

0

High-throughput

0.249

Low

1446824

SAE2
SUMO-activating enzyme subunit 2

1

0

High-throughput

0.249

Low

690726

AOFB
Amine oxidase [flavin-containing] B

1

0

High-throughput

0.232

Low

934031

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.232

Low

1188020

GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

1

0

High-throughput

0.232

Low

1211967

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low

1428473

REXO4
RNA exonuclease 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025