Interactor 1: HMDH (P04035)
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)
Gene: HMGCR

Interactor 2: PTHD3 (Q3KNS1)
Patched domain-containing protein 3 (Patched-related protein)
Gene: PTCHD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Patched~Sterol-sensing
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 888
Hs

1 954
+ Hs
+ Sc
+ Sc
+ Dm
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024