HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 464 Hs			1 305
+	Hs
		373290 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61
+	Hs
		406466 MYCN_HUMAN (1-464): 4.72e-90: 283: 100.00		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		371397 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Hs
		406479 MYCN_HUMAN (1-464): 4.72e-90: 283: 100.00		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Mm
		373704 MYC_MOUSE (5-463): 3.36e-72: 237: 33.95		FBXW7_MOUSE (91-303): 2.31e-64: 216: 24.30
+	Hs
		372767 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		405975 MYCN_HUMAN (1-464): 4.72e-90: 283: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		372801 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		371643 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		787890 SRBP1_HUMAN (86-464): 1.21e-35: 142: 14.25		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Mm
		1189859 SRBP2_MOUSE (138-459): 1.1e-31: 131: 15.11		FBXW7_MOUSE (91-303): 2.31e-64: 216: 24.30
+	Hs
		406801 MYCN_HUMAN (1-464): 4.72e-90: 283: 100.00		WDR3_HUMAN (6-218): 4.84e-10: 62.4: 25.56
+	Mm
		1353851 SRBP1_MOUSE (91-464): 1.09e-30: 128: 16.45		FBXW7_MOUSE (91-303): 2.31e-64: 216: 24.30
+	Hs
		209181 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68
+	Hs
		373187 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		GBB4_HUMAN (59-302): 1.04e-12: 69.3: 22.00
+	Hs
		373500 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		WDR3_HUMAN (6-218): 4.84e-10: 62.4: 25.56
+	Hs
		371880 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93
+	Hs
		284911 MYC_HUMAN (7-463): 2.15e-69: 229: 34.16		TAF5L_HUMAN (24-208): 1.34e-09: 60.8: 25.76
+	Hs
		648344 USF1_HUMAN (240-463): 1.08e-29: 119: 18.70		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		284921 MYCL_HUMAN (19-463): 3.39e-35: 136: 25.28		TAF5L_HUMAN (24-208): 1.34e-09: 60.8: 25.76