HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRI65 (Q6PJ69)
E3 ubiquitin-protein ligase TRIM65 (EC 2.3.2.27) (Tripartite motif-containing protein 65)
Gene: TRIM65

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	27012201, 30454706, 27249653
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 517
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (3-503): 1.96e-131: 393: 21.94
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (3-502): 5e-129: 385: 22.46
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (3-510): 6.09e-122: 369: 20.77
+	Hs
		386725 P53_HUMAN (1-393): 0: 619: 100.00		TRI25_HUMAN (6-503): 8.9e-99: 312: 22.58
+	Hs
		386960 P53_HUMAN (1-393): 0: 619: 100.00		TRI72_HUMAN (2-512): 2.84e-99: 309: 24.01
+	Hs
		387032 P53_HUMAN (1-393): 0: 619: 100.00		TRI69_HUMAN (4-503): 3.28e-95: 299: 20.00
+	Hs
		262148 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (10-224): 5.09e-16: 83.2: 28.70