HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRAF7 (Q6Q0C0)
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.-) (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)
Gene: TRAF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34775479, 38580884
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0008270 - zinc ion binding GO:0043525 - positive regulation of neuron apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 670
+	Hs
		386793 P53_HUMAN (1-393): 0: 619: 100.00		TAF5_HUMAN (98-669): 5.6e-83: 280: 14.17
+	Hs
		387771 P53_HUMAN (1-393): 0: 619: 100.00		FBW1A_HUMAN (175-586): 2.32e-60: 214: 15.99
+	Hs
		387700 P53_HUMAN (1-393): 0: 619: 100.00		FBW1B_HUMAN (181-586): 1.61e-59: 210: 15.51
+	Hs
		387246 P53_HUMAN (1-393): 0: 619: 100.00		FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60
+	Hs
		386436 P53_HUMAN (1-393): 0: 619: 100.00		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Hs
		1330016 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		FBW1A_HUMAN (175-586): 2.32e-60: 214: 15.99
+	Hs
		1281386 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60