HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: SLAF1 (Q13291)
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)
Gene: SLAMF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12545174
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 537 Hs			1 335
+	Mm
		763408 FYN_MOUSE (1-537): 0: 642: 99.44		SLAF1_MOUSE (1-335): 1.89e-69: 222: 59.77
+	Hs
		454828 FGR_HUMAN (1-536): 0: 581: 69.82		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Hs
		412347 FYN_HUMAN (1-537): 0: 643: 100.00		CD244_HUMAN (23-331): 5e-50: 172: 19.12
+	Hs
		411939 FYN_HUMAN (1-537): 0: 643: 100.00		CD2_HUMAN (14-323): 1.49e-47: 165: 18.79
+	Hs
		523136 SRC_HUMAN (1-537): 0: 598: 68.21		CD244_HUMAN (23-331): 5e-50: 172: 19.12
+	Hs
		433317 YES_HUMAN (1-537): 0: 591: 71.61		CXAR_HUMAN (10-334): 1.04e-51: 176: 13.68
+	Hs
		507818 SRC_HUMAN (1-537): 0: 598: 68.21		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		523015 SRC_HUMAN (1-537): 0: 598: 68.21		CEA21_HUMAN (7-295): 5.06e-49: 167: 17.51
+	Hs
		433229 YES_HUMAN (1-537): 0: 591: 71.61		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		412008 FYN_HUMAN (1-537): 0: 643: 100.00		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		411547 LCK_HUMAN (40-535): 0: 551: 57.60		CD2_HUMAN (14-323): 1.49e-47: 165: 18.79
+	Hs
		433691 LYN_HUMAN (1-535): 0: 535: 54.48		CXAR_HUMAN (10-334): 1.04e-51: 176: 13.68
+	Hs
		411818 LCK_HUMAN (40-535): 0: 551: 57.60		SLAF6_HUMAN (13-330): 2.04e-43: 154: 18.04
+	Hs
		411561 LCK_HUMAN (40-535): 0: 551: 57.60		CD48_HUMAN (35-256): 1.1e-43: 152: 23.66
+	Hs
		522773 SRC_HUMAN (1-537): 0: 598: 68.21		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Hs
		789096 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		SLAF5_HUMAN (15-334): 6.3e-54: 181: 21.21
+	Hs
		507897 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		522764 SRC_HUMAN (1-537): 0: 598: 68.21		CD33_HUMAN (102-211): 9.8e-11: 64.1: 23.93
+	Hs
		416917 ITK_HUMAN (4-526): 5.88e-165: 483: 31.90		CD2_HUMAN (14-323): 1.49e-47: 165: 18.79
+	Hs
		433573 LYN_HUMAN (1-535): 0: 535: 54.48		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29