Interactor 1: ECHP (P07896)
Peroxisomal bifunctional enzyme (PBE) (PBFE) (Multifunctional enzyme 1) (MFE1) (Multifunctional protein 1) (MFP1) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Gene: Ehhadh

Interactor 2: ECHP (P07896)
Peroxisomal bifunctional enzyme (PBE) (PBFE) (Multifunctional enzyme 1) (MFE1) (Multifunctional protein 1) (MFP1) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Gene: Ehhadh

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 23351063
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 3HCDH~3HCDH, 3HCDH~3HCDH_N, 3HCDH~ECH_1, 3HCDH_N~3HCDH_N, 3HCDH_N~ECH_1, ECH_1~ECH_1
Common GO terms GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004165 - delta(3)-delta(2)-enoyl-CoA isomerase activity
GO:0004300 - enoyl-CoA hydratase activity
GO:0005777 - peroxisome
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 722
Rn

1 722
+ Zm
+ Hs
+ Hs
+ Ce
+ Mt
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024