Interactor 1: ITA2B (P08514)
Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]
Gene: ITGA2B

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 25849143
Identification Methods nuclear magnetic resonance, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Filamin~Integrin_alpha
Common GO terms GO:0001525 - angiogenesis
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0070062 - extracellular exosome
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1039
Hs

1 2647
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024