Protein: IL3RA
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)

Gene: IL3RA
Organism: Homo sapiens
Interactions: 55
UniProt ID: P26951

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0004912 - interleukin-3 receptor activity
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475236

IL3
Interleukin-3

3

1

Small-scale

0.884

High

658849

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

18

High-throughput

0.691

High

689935

IL3RB
Cytokine receptor common subunit beta

1

19

Small-scale

0.618

High

328632

VAMP5
Vesicle-associated membrane protein 5

2

2

High-throughput

0.606

High

689941

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.584

High

155438

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.580

High

689939

EMP3
Epithelial membrane protein 3

2

0

High-throughput

0.580

High

689943

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

689949

TMM65
Transmembrane protein 65

2

0

High-throughput

0.580

High

689955

CLD19
Claudin-19

2

0

High-throughput

0.580

High

689962

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

689969

PAQR5
Membrane progestin receptor gamma

2

0

High-throughput

0.580

High

689970

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

335538

BMP10
Bone morphogenetic protein 10

2

4

High-throughput

0.553

High

689942

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

1

High-throughput

0.541

High

189423

STX7
Syntaxin-7

1

2

High-throughput

0.536

High

541350

FGFR1
Fibroblast growth factor receptor 1

1

19

High-throughput

0.536

High

641120

FGFR2
Fibroblast growth factor receptor 2

1

19

High-throughput

0.536

High

689946

S22A6
Solute carrier family 22 member 6

1

1

High-throughput

0.536

High

689948

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

10

High-throughput

0.536

High

689952

S39AB
Zinc transporter ZIP11

1

2

High-throughput

0.536

High

689963

ULBP3
UL16-binding protein 3

1

7

High-throughput

0.536

High

689971

PCD10
Protocadherin-10

1

4

High-throughput

0.536

High

603171

KPCA
Protein kinase C alpha type

1

9

High-throughput

0.515

High

689958

LNX1
E3 ubiquitin-protein ligase LNX

1

9

High-throughput

0.494

High

689966

SGK2
Serine/threonine-protein kinase Sgk2

1

7

High-throughput

0.494

High

689937

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.489

High

689956

NEDD1
Protein NEDD1

1

1

High-throughput

0.489

High

689951

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

440383

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.479

High

593915

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

618983

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

7

High-throughput

0.479

High

689968

CISH
Cytokine-inducible SH2-containing protein

1

20

Small-scale

0.479

High

63639

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

689940

1433G
14-3-3 protein gamma

1

6

High-throughput

0.470

High

689944

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.470

High

689957

LMO3
LIM domain only protein 3

1

2

High-throughput

0.470

High

689961

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.470

High

689938

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.437

High

689950

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

1

Small-scale

0.437

High

689947

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

689953

SYS1
Protein SYS1 homolog

2

0

High-throughput

0.316

High

689954

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

689959

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

689960

GIMA1
GTPase IMAP family member 1

2

0

High-throughput

0.316

High

689973

SERP1
Stress-associated endoplasmic reticulum protein 1

2

0

High-throughput

0.316

High

443192

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.282

High

689934

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.282

High

689945

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

0

High-throughput

0.282

High

689965

FOXP1
Forkhead box protein P1

1

0

High-throughput

0.282

High

689972

SAE1
SUMO-activating enzyme subunit 1

1

0

High-throughput

0.282

High

213565

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.279

Low

689964

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

689967

GPBL1
Vasculin-like protein 1

1

0

High-throughput

0.279

Low

689936

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025