Protein: IL3RB
Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)

Gene: IL3RB, CSF2RB
Organism: Homo sapiens
Interactions: 36
UniProt ID: P32927

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0007585 - respiratory gaseous exchange by respiratory system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

403271

CSF2
Granulocyte-macrophage colony-stimulating factor

3

2

Small-scale

0.840

High

475237

IL3
Interleukin-3

3

1

Small-scale

0.834

High

424329

IL5
Interleukin-5

2

1

Small-scale

0.776

High

748679

IL5RA
Interleukin-5 receptor subunit alpha

2

17

Small-scale

0.776

High

748680

PTN11
Tyrosine-protein phosphatase non-receptor type 11

5

20

Small-scale

0.713

High

253309

JAK2
Tyrosine-protein kinase JAK2

5

20

Small-scale

0.711

High

711250

SHC1
SHC-transforming protein 1

4

20

Small-scale

0.683

High

711040

PTN6
Tyrosine-protein phosphatase non-receptor type 6

3

20

Small-scale

0.672

High

658640

JAK1
Tyrosine-protein kinase JAK1

3

20

Small-scale

0.640

High

584630

CSF2R
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

1

19

Small-scale

0.618

High

689935

IL3RA
Interleukin-3 receptor subunit alpha

1

19

Small-scale

0.618

High

193217

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.584

High

748670

IL3RB
Cytokine receptor common subunit beta

1

15

Small-scale

0.575

High

748677

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.569

High

463369

LYN
Tyrosine-protein kinase Lyn

2

14

Small-scale

0.563

High

431726

ITB1
Integrin beta-1

1

2

Small-scale

0.561

High

539954

BCR
Breakpoint cluster region protein

1

4

Small-scale

0.536

High

748678

RACK1
Small ribosomal subunit protein RACK1

1

6

Small-scale

0.523

High

748674

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

3

Small-scale

0.516

High

699610

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

Small-scale

0.484

High

427811

ICAM1
Intercellular adhesion molecule 1

1

7

Small-scale

0.479

High

436617

KPCB
Protein kinase C beta type

1

5

Small-scale

0.479

High

440407

FYN
Tyrosine-protein kinase Fyn

1

14

Small-scale

0.479

High

748671

VGFR2
Vascular endothelial growth factor receptor 2

1

9

Small-scale

0.479

High

748672

STAT3
Signal transducer and activator of transcription 3

1

19

Small-scale

0.479

High

748675

CEBPA
CCAAT/enhancer-binding protein alpha

1

10

Small-scale

0.479

High

748676

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.479

High

748682

CEBPE
CCAAT/enhancer-binding protein epsilon

1

8

Small-scale

0.479

High

748684

TRAF6
TNF receptor-associated factor 6

1

7

Small-scale

0.479

High

748683

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

728053

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

Small-scale

0.445

High

748673

STA5A
Signal transducer and activator of transcription 5A

1

19

Small-scale

0.445

High

167834

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

4

Small-scale

0.439

High

606316

CEBPB
CCAAT/enhancer-binding protein beta

1

8

Small-scale

0.437

High

748681

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.292

High


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Last updated: 11Aug2025