HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27716508, 16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 568
+	Hs
		475742 UBC_HUMAN (1-685): 0: 846: 100.00		KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88
+	Hs
		476029 UBC_HUMAN (1-685): 0: 846: 100.00		KLHL7_HUMAN (19-563): 2.02e-155: 459: 32.19
+	Hs
		476473 UBC_HUMAN (1-685): 0: 846: 100.00		KLH28_HUMAN (15-565): 1.89e-155: 458: 37.77
+	Hs
		476498 UBC_HUMAN (1-685): 0: 846: 100.00		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Rn
		1144236 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KLH17_RAT (11-566): 1.56e-162: 479: 40.75
+	Mm
		477071 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KEAP1_MOUSE (8-564): 7.68e-162: 476: 35.52
+	Mm
		476912 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KLHL2_MOUSE (13-567): 1.77e-157: 464: 41.36
+	Mm
		476979 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KLH28_MOUSE (15-565): 2.15e-154: 456: 37.77
+	Hs
		397998 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		KLH26_HUMAN (365-568): 5.54e-30: 126: 23.26