HitPredict

Interactor 1: GNAI1 (B2RSH2)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Interactor 2: SSR3 (P30935)
Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SSR-28)
Gene: Sstr3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38187761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 354 Mm			1 428
+	Mm
		475860 GNAI2_MOUSE (1-354): 6.46e-178: 499: 87.89		SSR3_MOUSE (1-428): 7.23e-101: 308: 100.00
+	Hs
		458371 GNAI1_HUMAN (1-354): 0: 516: 100.00		ADRB2_HUMAN (4-408): 5.63e-83: 262: 19.34
+	Hs
		458244 GNAI3_HUMAN (1-354): 0: 507: 93.79		ADRB2_HUMAN (4-408): 5.63e-83: 262: 19.34
+	Mm
		267012 GNAZ_MOUSE (1-353): 1.53e-161: 457: 66.95		SSR3_MOUSE (1-428): 7.23e-101: 308: 100.00
+	Hs
		418567 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		ADRB2_HUMAN (4-408): 5.63e-83: 262: 19.34
+	Hs
		458271 GNAT2_HUMAN (1-354): 3.22e-172: 484: 69.49		ADRB2_HUMAN (4-408): 5.63e-83: 262: 19.34
+	Hs
		482579 GNAO_HUMAN (1-354): 1.39e-175: 493: 72.11		OPRM_HUMAN (2-373): 3.28e-76: 244: 31.03
+	Hs
		418612 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		OPRD_HUMAN (7-367): 7.98e-71: 229: 33.78
+	Hs
		482584 GNAO_HUMAN (1-354): 1.39e-175: 493: 72.11		OPRD_HUMAN (7-367): 7.98e-71: 229: 33.78
+	Hs
		716010 GNA11_HUMAN (1-353): 1.37e-162: 460: 51.13		CXCR4_HUMAN (43-342): 3.75e-82: 258: 27.36
+	Hs
		733309 GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26		CCR1_HUMAN (30-376): 1.2e-73: 236: 22.19
+	Hs
		956863 GNA13_HUMAN (2-353): 2.27e-155: 442: 39.17		CXCR4_HUMAN (43-342): 3.75e-82: 258: 27.36
+	Hs
		720653 GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26		AGTR1_HUMAN (33-370): 2.3e-70: 227: 25.50
+	Hs
		733349 GNA13_HUMAN (2-353): 2.27e-155: 442: 39.17		CCR1_HUMAN (30-376): 1.2e-73: 236: 22.19
+	Hs
		458370 GNAS2_HUMAN (1-354): 4.73e-143: 412: 38.23		ADRB2_HUMAN (4-408): 5.63e-83: 262: 19.34
+	Hs
		893516 GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26		KISSR_HUMAN (30-336): 4.91e-38: 144: 34.51
+	Hs
		721452 GNA15_HUMAN (4-354): 1.17e-149: 428: 42.70		KISSR_HUMAN (30-336): 4.91e-38: 144: 34.51
+	Hs
		989805 GNAS2_HUMAN (1-354): 4.73e-143: 412: 38.23		RL3R1_HUMAN (46-361): 2.32e-39: 149: 33.14