HitPredict

Interactor 1: GNAI3 (P08753)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: AA3R (P28647)
Adenosine receptor A3 (TGPCR1)
Gene: Adora3

Species: Rattus norvegicus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	7622506
Identification Methods	coimmunoprecipitation, experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Rn			1 320
+	Hs
		458371 GNAI1_HUMAN (1-354): 2.96e-179: 502: 93.50		ADRB2_HUMAN (4-305): 5.4e-73: 232: 24.54
+	Hs
		458244 GNAI3_HUMAN (1-354): 1.25e-176: 495: 98.59		ADRB2_HUMAN (4-305): 5.4e-73: 232: 24.54
+	Hs
		418602 GNAI2_HUMAN (1-354): 1.55e-174: 490: 85.35		AA1R_HUMAN (7-317): 1.32e-74: 233: 46.56
+	Hs
		418567 GNAI2_HUMAN (1-354): 1.55e-174: 490: 85.35		ADRB2_HUMAN (4-305): 5.4e-73: 232: 24.54
+	Hs
		989839 GNAI1_HUMAN (1-354): 2.96e-179: 502: 93.50		MTR1L_HUMAN (2-305): 6.12e-65: 216: 18.65
+	Rn
		418562 GNAI2_RAT (1-354): 7.23e-174: 489: 85.07		AA3R_RAT (1-320): 4.34e-70: 222: 100.00
+	Hs
		458271 GNAT2_HUMAN (1-354): 3.54e-167: 471: 68.64		ADRB2_HUMAN (4-305): 5.4e-73: 232: 24.54
+	Hs
		418612 GNAI2_HUMAN (1-354): 1.55e-174: 490: 85.35		OPRD_HUMAN (7-320): 2.78e-64: 208: 20.56
+	Hs
		482579 GNAO_HUMAN (1-354): 5.01e-171: 481: 71.27		OPRM_HUMAN (4-320): 6.32e-67: 216: 18.89
+	Hs
		482584 GNAO_HUMAN (1-354): 5.01e-171: 481: 71.27		OPRD_HUMAN (7-320): 2.78e-64: 208: 20.56
+	Bt
		388110 GNAT1_BOVIN (1-354): 3.06e-164: 464: 64.41		OPSD_BOVIN (11-318): 5.78e-65: 210: 16.35
+	Hs
		618433 GNAZ_HUMAN (1-353): 4.19e-156: 443: 66.95		DRD5_HUMAN (31-316): 2.3e-66: 217: 23.28
+	Hs
		641907 GNA13_HUMAN (2-353): 3.58e-153: 437: 38.33		DRD5_HUMAN (31-316): 2.3e-66: 217: 23.28
+	Hs
		458370 GNAS2_HUMAN (1-353): 1.16e-139: 403: 38.42		ADRB2_HUMAN (4-305): 5.4e-73: 232: 24.54
+	Hs
		641904 GNAS2_HUMAN (1-353): 1.16e-139: 403: 38.42		DRD5_HUMAN (31-316): 2.3e-66: 217: 23.28
+	Hs
		880902 GNAI1_HUMAN (1-354): 2.96e-179: 502: 93.50		MTR1B_HUMAN (29-301): 2.72e-18: 86.3: 28.87
+	Hs
		475919 GNAI3_HUMAN (1-354): 1.25e-176: 495: 98.59		MTR1B_HUMAN (29-301): 2.72e-18: 86.3: 28.87
+	Hs
		418621 GNAI2_HUMAN (1-354): 1.55e-174: 490: 85.35		MTR1B_HUMAN (29-301): 2.72e-18: 86.3: 28.87
+	Hs
		880901 GNAS2_HUMAN (1-353): 1.16e-139: 403: 38.42		MTR1B_HUMAN (29-301): 2.72e-18: 86.3: 28.87
+	Hs
		641905 GNA12_HUMAN (19-350): 9.12e-87: 268: 42.14		DRD5_HUMAN (31-316): 2.3e-66: 217: 23.28