Interactor 1: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1
Interactor 2: MTR1L (Q13585)
Melatonin-related receptor (G protein-coupled receptor 50) (H9) [Cleaved into: C-terminal domain]
Gene: GPR50
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16778767 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~G-alpha |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
