HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: PSB2 (Q9VQE5)
Probable proteasome subunit beta type-2
Gene: Prosbeta4R2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019774 - proteasome core complex, beta-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 224 Dm			1 210
+	Hs
		700503 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB2_HUMAN (3-197): 9.3e-86: 253: 44.10
+	Sp
		721233 PSB5_SCHPO (12-199): 4.04e-83: 250: 26.98		PSA5_SCHPO (3-207): 6.33e-69: 212: 16.43
+	Sc
		668369 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PSB5_YEAST (2-207): 1.29e-69: 215: 18.93
+	Hs
		700431 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB8_HUMAN (2-207): 1.01e-71: 220: 19.42
+	Sc
		721254 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PSB5_YEAST (2-207): 1.29e-69: 215: 18.93
+	Hs
		700497 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB5_HUMAN (1-206): 1.01e-70: 217: 18.45
+	Dm
		47762 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q7K148_DROME (2-207): 1.42e-70: 218: 21.85
+	Hs
		165266 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSA7_HUMAN (2-206): 8.82e-68: 209: 16.75
+	Hs
		700494 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSA5_HUMAN (3-208): 6.15e-68: 209: 16.43
+	Sc
		645127 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PSB4_YEAST (3-199): 1.65e-65: 202: 32.32
+	Hs
		700538 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB7_HUMAN (5-208): 6.74e-67: 208: 23.53
+	Hs
		681575 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSA4_HUMAN (2-205): 2.99e-66: 206: 16.82
+	Sc
		645163 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PSB4_YEAST (3-199): 1.65e-65: 202: 32.32
+	Hs
		700499 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB10_HUMAN (5-198): 7.29e-65: 203: 19.59
+	Dm
		47773 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q8T8U1_DROME (3-207): 2.17e-66: 204: 43.90
+	Sc
		668383 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PSB1_YEAST (5-193): 7.1e-32: 116: 19.05
+	Sc
		800838 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PSB1_YEAST (5-193): 7.1e-32: 116: 19.05
+	Ph
		237460 PSA_PYRHO (4-213): 1.21e-78: 238: 18.14		PSB1_PYRHO (5-192): 1.12e-28: 108: 24.34
+	Hs
		633603 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PSB1_HUMAN (5-192): 9.38e-27: 104: 23.86