HitPredict

Interactor 1: SWI6 (P09959)
Regulatory protein SWI6 (Cell-cycle box factor subunit SWI6) (MBF subunit P90) (Trans-acting activator of HO endonuclease gene)
Gene: SWI6

Interactor 2: CDC14 (Q00684)
Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)
Gene: CDC14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	14993267, 28758351, 21179020
Identification Methods	enzymatic study, x-ray crystallography, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Sc			1 551
+	Sc
		813345 MBP1_YEAST (259-794): 3.12e-93: 312: 19.56		CDC14_YEAST (1-551): 0: 564: 100.00
+	Sc
		671547 SWI4_YEAST (238-767): 5.32e-72: 257: 18.50		CDC14_YEAST (1-551): 0: 564: 100.00
+	Sp
		834927 RES2_SCHPO (160-784): 1.04e-64: 230: 19.24		FLP1_SCHPO (3-548): 4.92e-156: 458: 40.00
+	Sp
		753777 RES1_SCHPO (204-749): 6.32e-57: 208: 18.34		FLP1_SCHPO (3-548): 4.92e-156: 458: 40.00
+	Sp
		376451 CDC10_SCHPO (237-799): 2.07e-52: 197: 26.61		FLP1_SCHPO (3-548): 4.92e-156: 458: 40.00
+	Hs
		177146 ANR28_HUMAN (58-560): 3.67e-44: 174: 13.30		CC14B_HUMAN (4-464): 8.98e-155: 453: 29.55
+	Hs
		254391 ANR52_HUMAN (10-597): 1.04e-41: 166: 11.88		CC14B_HUMAN (4-464): 8.98e-155: 453: 29.55
+	Hs
		254388 ANR44_HUMAN (20-502): 1.95e-34: 143: 13.29		CC14B_HUMAN (4-464): 8.98e-155: 453: 29.55
+	Hs
		254448 ANR50_HUMAN (286-792): 4.61e-32: 136: 11.26		CC14B_HUMAN (4-464): 8.98e-155: 453: 29.55
+	Hs
		951852 TNKS2_HUMAN (210-690): 1.19e-58: 218: 12.99		PTEN_HUMAN (152-540): 3.28e-74: 243: 14.53
+	Hs
		332394 TNKS1_HUMAN (154-689): 2.14e-56: 212: 12.22		PTEN_HUMAN (152-540): 3.28e-74: 243: 14.53
+	Hs
		1311390 ANKH1_HUMAN (154-491): 4.97e-33: 140: 11.50		DUS16_HUMAN (192-546): 2.5e-65: 226: 15.39
+	Hs
		177306 ANR28_HUMAN (58-560): 3.67e-44: 174: 13.30		DUS15_HUMAN (202-497): 6.24e-47: 167: 13.00
+	Hs
		277422 RAI14_HUMAN (268-799): 1.98e-51: 196: 12.48		TP4A3_HUMAN (188-362): 3.28e-40: 145: 23.20
+	Hs
		1333076 ANR52_HUMAN (10-597): 1.04e-41: 166: 11.88		DUS15_HUMAN (202-497): 6.24e-47: 167: 13.00
+	Hs
		58687 ANR28_HUMAN (58-560): 3.67e-44: 174: 13.30		PTPC1_HUMAN (162-371): 6.18e-37: 147: 18.06
+	Hs
		1091823 ANR52_HUMAN (10-597): 1.04e-41: 166: 11.88		TP4A2_HUMAN (188-355): 2.36e-39: 143: 27.01
+	Hs
		171784 KDIS_HUMAN (445-803): 1.67e-32: 138: 9.76		GAK_HUMAN (115-347): 3.72e-43: 167: 14.35
+	Hs
		506978 POTEI_HUMAN (242-740): 5.75e-26: 117: 14.54		SSH1_HUMAN (212-450): 7.62e-41: 160: 10.93
+	Hs
		506986 POTEI_HUMAN (242-740): 5.75e-26: 117: 14.54		DUS23_HUMAN (173-334): 4.62e-36: 133: 20.99