Protein: SWI4
Regulatory protein SWI4 (Cell-cycle box factor subunit SWI4) (Protein ART1)

Gene: SWI4
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P25302

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488920

SWI6
Regulatory protein SWI6

16

18

Small-scale

0.987

High

671548

SLT2
Mitogen-activated protein kinase SLT2/MPK1

3

6

Small-scale

0.891

High

646308

RAD53
Serine/threonine-protein kinase RAD53

3

5

Small-scale

0.847

High

364356

CDK1
Cyclin-dependent kinase 1

3

5

Small-scale

0.835

High

671498

SWI4
Regulatory protein SWI4

2

15

Small-scale

0.777

High

671574

WHI5
G1-specific transcriptional repressor WHI5

9

1

Small-scale

0.750

High

671517

MSA2
Putative transcriptional activator MSA2

3

2

Small-scale

0.633

High

671565

MSA1
G1-specific transcription factors activator MSA1

3

2

Small-scale

0.633

High

671528

MBP1
Transcription factor MBP1

1

18

Small-scale

0.618

High

667069

CG22
G2/mitotic-specific cyclin-2

2

2

Small-scale

0.612

High

671518

SRL3
Protein SRL3

2

1

Small-scale

0.584

High

671514

BCK2
Protein BCK2

2

0

High-throughput

0.576

High

671568

YL053
Putative uncharacterized protein YLR053C

1

1

Small-scale

0.561

High

359155

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.536

High

671530

PCL7
PHO85 cyclin-7

1

0

High-throughput

0.493

High

613816

TEC1
Ty transcription activator TEC1

1

3

Small-scale

0.479

High

671501

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

671507

SPT16
FACT complex subunit SPT16

1

1

Small-scale

0.479

High

671516

SPT10
Protein SPT10

1

2

High-throughput

0.479

High

671527

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

671557

POB3
FACT complex subunit POB3

1

1

Small-scale

0.479

High

671570

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.479

High

671569

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

585470

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

671522

STB5
Protein STB5

1

4

High-throughput

0.457

High

381416

H2B2
Histone H2B.2

1

11

High-throughput

0.445

High

381894

H4
Histone H4

1

5

High-throughput

0.445

High

392283

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

419614

H2A2
Histone H2A.2

1

8

High-throughput

0.445

High

445315

CDC31
Cell division control protein 31

1

1

High-throughput

0.445

High

481496

HSP73
Heat shock protein SSA3

1

7

High-throughput

0.445

High

523147

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

548751

MCM1
Pheromone receptor transcription factor

1

2

High-throughput

0.445

High

561423

TBP
TATA-box-binding protein

1

1

High-throughput

0.445

High

614797

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

8

High-throughput

0.445

High

664409

MCM3
DNA replication licensing factor MCM3

1

7

High-throughput

0.445

High

670215

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.445

High

671499

RSC6
Chromatin structure-remodeling complex protein RSC6

1

4

High-throughput

0.445

High

671502

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.445

High

671503

MCM5
Minichromosome maintenance protein 5

1

8

High-throughput

0.445

High

671505

BTAF1
TATA-binding protein-associated factor MOT1

1

12

High-throughput

0.445

High

671506

PRP19
Pre-mRNA-processing factor 19

1

12

Small-scale

0.445

High

671508

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

671509

SWI3
SWI/SNF complex subunit SWI3

1

11

High-throughput

0.445

High

671510

STH1
Nuclear protein STH1/NPS1

1

7

High-throughput

0.445

High

671511

CHD1
Chromo domain-containing protein 1

1

5

High-throughput

0.445

High

671513

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

2

High-throughput

0.445

High

671520

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

15

High-throughput

0.445

High

671521

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

11

High-throughput

0.445

High

671523

RSC30
Chromatin structure-remodeling complex protein RSC30

1

2

High-throughput

0.445

High

671524

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

4

High-throughput

0.445

High

671525

SKN7
Transcription factor SKN7

1

2

High-throughput

0.445

High

671532

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

2

High-throughput

0.445

High

671534

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.445

High

671538

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.445

High

671539

MCM6
DNA replication licensing factor MCM6

1

7

High-throughput

0.445

High

671540

ITC1
Imitation switch two complex protein 1

1

1

High-throughput

0.445

High

671541

RT102
Regulator of Ty1 transposition protein 102

1

1

High-throughput

0.445

High

671542

H1
Histone H1

1

1

High-throughput

0.445

High

671543

SNF12
Transcription regulatory protein SNF12

1

4

High-throughput

0.445

High

671544

ACT
Actin

1

20

High-throughput

0.445

High

671545

H3
Histone H3

1

15

High-throughput

0.445

High

671546

ARP4
Actin-related protein 4

1

19

High-throughput

0.445

High

671547

CDC14
Tyrosine-protein phosphatase CDC14

1

20

High-throughput

0.445

High

671549

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

14

High-throughput

0.445

High

671552

DIG1
Down-regulator of invasive growth 1

1

1

High-throughput

0.445

High

671553

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

1

High-throughput

0.445

High

671554

TAF8
Transcription initiation factor TFIID subunit 8

1

1

High-throughput

0.445

High

671555

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

3

High-throughput

0.445

High

671556

RUVB1
RuvB-like protein 1

1

8

High-throughput

0.445

High

671558

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.445

High

671559

ARP9
Actin-like protein ARP9

1

20

High-throughput

0.445

High

671560

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

1

High-throughput

0.445

High

671562

RSC3
Chromatin structure-remodeling complex protein RSC3

1

2

High-throughput

0.445

High

671564

RSC58
Chromatin structure-remodeling complex protein RSC58

1

1

High-throughput

0.445

High

671566

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

11

High-throughput

0.445

High

671572

ARP8
Actin-like protein ARP8

1

18

High-throughput

0.445

High

671573

ARP7
Actin-related protein 7

1

19

High-throughput

0.445

High

671575

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.445

High

671576

H2AZ
Histone H2A.Z

1

7

High-throughput

0.445

High

360949

CCPR
Cytochrome c peroxidase, mitochondrial

1

1

High-throughput

0.437

High

671519

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

2

High-throughput

0.437

High

671567

AP3D
AP-3 complex subunit delta

1

5

High-throughput

0.437

High

553514

PDR1
Transcription factor PDR1

1

0

High-throughput

0.426

High

617769

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.426

High

652851

TRX2
Thioredoxin-2

1

0

High-throughput

0.426

High

671504

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.426

High

671512

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.426

High

671515

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.426

High

671526

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

671533

IES1
Ino eighty subunit 1

1

0

High-throughput

0.426

High

671537

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

671550

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

671571

RLM1
Transcription factor RLM1

1

0

High-throughput

0.426

High

149196

FOB1
DNA replication fork-blocking protein FOB1

1

1

High-throughput

0.407

High

671529

HSP7E
Heat shock protein SSC3, mitochondrial

1

8

High-throughput

0.407

High

671531

DJP1
DnaJ-like protein 1

1

5

High-throughput

0.407

High

671535

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.407

High

671536

NET1
Nucleolar protein NET1

1

2

High-throughput

0.407

High

671561

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

18

High-throughput

0.407

High

671563

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.407

High

671500

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.269

Low

569913

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

671551

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025