HitPredict

Interactor 1: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 457
+	Hs
		834915 RGS3_HUMAN (1-1198): 0: 953: 100.00		ZN397_HUMAN (78-329): 5.38e-31: 126: 7.66
+	Hs
		834904 RGS3_HUMAN (1-1198): 0: 953: 100.00		ZKSC8_HUMAN (393-452): 2.74e-15: 80: 10.45
+	Hs
		834933 RGS3_HUMAN (1-1198): 0: 953: 100.00		ZN629_HUMAN (75-420): 3.53e-11: 67.7: 7.21
+	Hs
		1336088 SMUF1_HUMAN (151-667): 1.41e-77: 274: 17.83		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		408685 KPCB_HUMAN (124-271): 2.1e-67: 242: 30.87		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Rn
		934617 KPCB_RAT (124-271): 1.46e-67: 243: 30.87		PDLI5_RAT (1-282): 2.39e-28: 119: 24.47
+	Hs
		408660 KPCB_HUMAN (124-271): 2.1e-67: 242: 30.87		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Mm
		593492 KPCA_MOUSE (125-271): 9.25e-69: 246: 29.73		LDB3_MOUSE (3-192): 9.19e-26: 112: 29.90
+	Mm
		934638 KPCB_MOUSE (124-271): 1.46e-67: 243: 30.87		LDB3_MOUSE (3-192): 9.19e-26: 112: 29.90
+	Hs
		816282 SMUF1_HUMAN (151-667): 1.41e-77: 274: 17.83		LIMS1_HUMAN (298-452): 6.05e-14: 74.3: 24.54
+	Mm
		930579 KPCG_MOUSE (81-272): 5.35e-62: 227: 31.61		LDB3_MOUSE (3-192): 9.19e-26: 112: 29.90
+	Hs
		782036 RGS2_HUMAN (1004-1193): 8.29e-62: 211: 46.84		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87