HitPredict

Interactor 1: HNRPL (P14866)
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Gene: HNRNPL

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 25192599, 29884807, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~RRM_5
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0043484 - regulation of RNA splicing
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 589
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024