HitPredict

Interactor 1: HNRPL (P14866)
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Gene: HNRNPL

Interactor 2: MATR3 (P43243)
Matrin-3
Gene: MATR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 29884807, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 847
+	Hs
		793840 MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64		MATR3_HUMAN (1-847): 0: 1198: 100.00
+	Hs
		516399 PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19		MATR3_HUMAN (1-847): 0: 1198: 100.00
+	Hs
		793940 PABP4_HUMAN (53-368): 1.3e-41: 161: 15.48		MATR3_HUMAN (1-847): 0: 1198: 100.00
+	Hs
		540901 HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00		PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86
+	Hs
		540886 HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00		HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09
+	Hs
		541080 HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00		HNRLL_HUMAN (392-640): 3.16e-69: 240: 15.94
+	Hs
		643554 HNRLL_HUMAN (31-587): 2.07e-86: 280: 48.93		PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86
+	Dm
		1181642 Q8IHH3_DROME (281-586): 9.53e-79: 256: 34.41		Q7KRS7_DROME (333-627): 1.62e-78: 268: 14.65
+	Hs
		1261871 HNRLL_HUMAN (31-587): 2.07e-86: 280: 48.93		HNRLL_HUMAN (392-640): 3.16e-69: 240: 15.94
+	Hs
		643443 MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64		PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86
+	Dm
		56217 A1ZBN3_DROME (303-586): 2.09e-78: 255: 37.72		Q95UI6_DROME (338-627): 8.93e-75: 262: 14.57
+	Hs
		321006 MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64		PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39
+	Hs
		794169 MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64		PTBP2_HUMAN (329-625): 1.45e-85: 284: 15.50
+	Hs
		516346 PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19		HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09
+	Hs
		643426 PTBP1_HUMAN (20-270): 3.87e-26: 114: 18.73		PTBP1_HUMAN (329-604): 1.42e-92: 304: 17.86
+	Dm
		90924 Q95UI6_DROME (31-585): 4.5e-66: 231: 21.59		E1JJ45_DROME (441-627): 7.99e-49: 182: 11.34
+	Hs
		320980 PTBP1_HUMAN (20-270): 3.87e-26: 114: 18.73		PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39
+	Hs
		793963 MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64		ZN638_HUMAN (650-843): 4.53e-20: 98.4: 22.97