Interactor 1: SYDC (P14868)
Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)
Gene: DARS1

Interactor 2: AIMP2 (Q13155)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)
Gene: AIMP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 32296183, 31792442, 35546148, 21900206, 25416956, 16189514, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AIMP2_LysRS_bd~tRNA-synt_2, Thioredoxin_16~tRNA-synt_2
Common GO terms GO:0005829 - cytosol
GO:0006412 - translation
GO:0016020 - membrane
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
GO:0065003 - protein-containing complex assembly
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 501
Hs

1 320
+ Cg
+ Hs
+ Dm

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Last updated: 15 Jul 2024