HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: BAZ1B (Q9UIG0)
Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)
Gene: BAZ1B

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	32518374, 31045206, 19092802
Identification Methods	affinity chromatography technology, enzymatic study, protein kinase assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 1483
+	Hs
		555681 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ2A_HUMAN (928-1448): 2.16e-77: 286: 19.06
+	Hs
		555569 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2A_HUMAN (1020-1442): 2.66e-47: 185: 13.24
+	Hs
		555570 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2B_HUMAN (917-1442): 2e-45: 180: 12.85
+	Hs
		555430 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		555609 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		RSF1_HUMAN (477-1311): 3.83e-39: 161: 12.77
+	Hs
		998866 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		391671 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		EP300_HUMAN (1229-1460): 7.94e-39: 161: 16.53
+	Hs
		555299 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		555434 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BPTF_HUMAN (1344-1440): 3.78e-27: 123: 31.96
+	Hs
		555661 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ1A_HUMAN (1267-1463): 1.71e-22: 107: 17.59
+	Hs
		631492 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		391554 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD2_HUMAN (1309-1450): 6.63e-28: 124: 21.53
+	Hs
		555470 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD3_HUMAN (1331-1447): 6.43e-21: 101: 22.69
+	Hs
		555528 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PB1_HUMAN (1361-1483): 7.39e-18: 92.5: 21.95
+	Hs
		244848 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		244634 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		244795 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		243783 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD4_HUMAN (1308-1470): 1.84e-22: 107: 21.82
+	Hs
		1067038 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD3_HUMAN (1331-1447): 6.43e-21: 101: 22.69
+	Hs
		391768 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PB1_HUMAN (1361-1483): 7.39e-18: 92.5: 21.95