HitPredict

Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12135703
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 672 Hs			1 586
+	Hs
		359636 KPCA_HUMAN (1-672): 0: 794: 100.00		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		408554 KPCB_HUMAN (1-664): 0: 749: 78.89		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Mm
		554876 KPCE_MOUSE (8-664): 0: 637: 44.76		LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37
+	Hs
		397132 KPCG_HUMAN (1-670): 0: 706: 68.94		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Mm
		554866 KPCE_MOUSE (8-664): 0: 637: 44.76		DESM_MOUSE (28-390): 6.47e-33: 133: 30.85
+	Mm
		554861 KPCE_MOUSE (8-664): 0: 637: 44.76		VIME_MOUSE (28-390): 1.46e-29: 123: 28.38
+	Mm
		682101 AKT1_MOUSE (243-660): 1.45e-155: 459: 37.36		LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37
+	Hs
		1055200 AKT3_HUMAN (283-660): 6.86e-156: 460: 40.46		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		681844 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		443354 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		443355 AKT2_HUMAN (242-660): 9.73e-156: 459: 39.13		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		535333 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Mm
		589625 KPCZ_MOUSE (22-86): 1.13e-10: 66.6: 38.46		VIME_MOUSE (28-390): 1.46e-29: 123: 28.38