HitPredict

Interactor 1: A1ZAN6 (A1ZAN6)
Rho guanine nucleotide exchange factor 2, isoform D (Rho guanine nucleotide exchange factor 2, isoform F)
Gene: RhoGEF2

Interactor 2: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 28923977, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Ras, PDZ~Ras, PH_16~Ras, Ras~RhoGEF
Common GO terms GO:0005737 - cytoplasm
GO:0007015 - actin filament organization
GO:0007349 - cellularization
GO:0007370 - ventral furrow formation
GO:0007374 - posterior midgut invagination
and 12 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2559
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Last updated: 11Aug2025