Interactor 1: A1ZAN6 (A1ZAN6)
Rho guanine nucleotide exchange factor 2, isoform D (Rho guanine nucleotide exchange factor 2, isoform F)
Gene: RhoGEF2
Interactor 2: CDC42 (P40793)
Cdc42 homolog (EC 3.6.5.2)
Gene: CDC42
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28923977 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~Ras, PDZ~Ras, PH_16~Ras, Ras~RhoGEF |
| Common GO terms | GO:0005737 - cytoplasm GO:0007015 - actin filament organization GO:0007349 - cellularization GO:0008360 - regulation of cell shape GO:0009611 - response to wounding and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025