HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CAD10 (Q9Y6N8)
Cadherin-10 (T2-cadherin)
Gene: CDH10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24722188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arm~CADH_Y-type_LIR
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0016342 - catenin complex GO:0016477 - cell migration GO:0045296 - cadherin binding and 1 others more... GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 788
+	Hs
		764581 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH6_HUMAN (1-788): 0: 823: 72.69
+	Hs
		577680 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH8_HUMAN (1-788): 0: 773: 57.70
+	Hs
		577607 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH2_HUMAN (21-784): 0: 653: 36.00
+	Hs
		555850 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH1_HUMAN (2-785): 0: 625: 32.46
+	Hs
		577720 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC2_HUMAN (33-777): 0: 621: 27.49
+	Hs
		577616 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH3_HUMAN (29-785): 0: 620: 31.96
+	Hs
		618223 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH2_HUMAN (21-784): 0: 653: 36.00
+	Hs
		577757 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC3_HUMAN (33-777): 0: 616: 28.48
+	Hs
		555906 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH1_HUMAN (2-785): 0: 625: 32.46
+	Hs
		646699 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH3_HUMAN (29-785): 0: 620: 31.96
+	Cl
		84231 CTNB1_CANLF (1-731): 3.56e-172: 515: 67.38		CADH1_CANLF (32-785): 0: 618: 34.07
+	Hs
		577728 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC1_HUMAN (27-776): 0: 570: 28.48
+	Hs
		577641 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH5_HUMAN (2-513): 3.62e-91: 304: 23.54
+	Mm
		937529 PLAK_MOUSE (1-745): 0: 552: 98.39		CADH5_MOUSE (2-513): 5.45e-90: 301: 23.60
+	Hs
		749752 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH5_HUMAN (2-513): 3.62e-91: 304: 23.54
+	Hs
		577938 PLAK_HUMAN (1-745): 0: 550: 100.00		X5DQT8_HUMAN (665-788): 1.78e-80: 259: 100.00
+	Mm
		580363 PLAK_MOUSE (1-745): 0: 552: 98.39		CADH2_MOUSE (1-479): 1.8e-60: 222: 20.62
+	Hs
		764580 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH4_HUMAN (1-485): 2.08e-72: 256: 19.81
+	Gg
		205901 O42486_CHICK (1-731): 1.07e-174: 522: 67.51		CADH2_CHICK (1-483): 1.65e-68: 245: 20.19
+	Rn
		1490147 CTNB1_RAT (1-731): 2.15e-172: 516: 67.38		CADH2_RAT (1-479): 4.05e-60: 221: 20.43