HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: X5DQT8 (X5DQT8)
Cadherin 10 type 2 isoform C
Gene: CDH10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	24722188
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~CADH_Y-type_LIR
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 243
+	Hs
		577937 PLAK_HUMAN (1-745): 0: 550: 100.00		CAD10_HUMAN (94-243): 4.17e-56: 192: 84.00
+	Hs
		577680 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH8_HUMAN (6-189): 2.03e-46: 166: 31.82
+	Hs
		577720 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC2_HUMAN (15-211): 8.56e-41: 150: 18.14
+	Hs
		577752 PLAK_HUMAN (1-745): 0: 550: 100.00		DSG2_HUMAN (2-195): 9.29e-40: 147: 18.66
+	Hs
		577757 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC3_HUMAN (25-211): 7e-40: 147: 18.05
+	Mm
		937529 PLAK_MOUSE (1-745): 0: 552: 98.39		CADH5_MOUSE (30-182): 5.89e-35: 133: 27.44
+	Hs
		577641 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH5_HUMAN (5-182): 8.21e-34: 130: 24.34
+	Hs
		577616 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH3_HUMAN (22-205): 9.37e-33: 127: 20.20
+	Hs
		764580 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH4_HUMAN (7-182): 4.53e-41: 151: 20.00
+	Cl
		84231 CTNB1_CANLF (1-731): 3.56e-172: 515: 67.38		CADH1_CANLF (28-198): 1e-40: 150: 20.00
+	Hs
		749752 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH5_HUMAN (5-182): 8.21e-34: 130: 24.34
+	Hs
		646699 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH3_HUMAN (22-205): 9.37e-33: 127: 20.20
+	Mm
		580363 PLAK_MOUSE (1-745): 0: 552: 98.39		CADH2_MOUSE (57-199): 1.49e-10: 62.7: 20.25
+	Hs
		577607 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH2_HUMAN (57-199): 9.55e-11: 63.1: 19.63
+	Hs
		577728 PLAK_HUMAN (1-745): 0: 550: 100.00		DSC1_HUMAN (61-181): 2.58e-10: 62: 20.00
+	Hs
		555850 PLAK_HUMAN (1-745): 0: 550: 100.00		CADH1_HUMAN (80-181): 8.8e-09: 57.3: 14.53
+	Gg
		205901 O42486_CHICK (1-731): 1.07e-174: 522: 67.51		CADH2_CHICK (57-181): 8.01e-11: 63.5: 20.00
+	Rn
		1490147 CTNB1_RAT (1-731): 2.15e-172: 516: 67.38		CADH2_RAT (57-199): 1.47e-10: 62.7: 20.25
+	Hs
		618223 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH2_HUMAN (57-199): 9.55e-11: 63.1: 19.63
+	Hs
		555906 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		CADH1_HUMAN (80-181): 8.8e-09: 57.3: 14.53