HitPredict

Interactor 1: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Myosin_head
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 970
+	Hs
		169131 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		533999 MLRV_HUMAN (9-165): 3e-55: 173: 58.23		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		1392661 MYL10_HUMAN (9-170): 1.35e-49: 160: 46.47		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		169171 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		169158 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		618655 ML12A_HUMAN (1-171): 7.98e-66: 200: 100.00		MYH11_HUMAN (2-965): 0: 1001: 26.34
+	Hs
		169066 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYH11_HUMAN (2-965): 0: 1001: 26.34
+	Hs
		534006 MLRV_HUMAN (9-165): 3e-55: 173: 58.23		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		169045 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYH7_HUMAN (2-934): 0: 1000: 26.13
+	Hs
		618654 ML12A_HUMAN (1-171): 7.98e-66: 200: 100.00		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		169065 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		618653 ML12A_HUMAN (1-171): 7.98e-66: 200: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Mm
		1223376 Q6ZWQ9_MOUSE (1-171): 1.8e-64: 196: 97.09		MYH10_MOUSE (2-965): 0: 1000: 26.14
+	Hs
		169064 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		666741 MYL9_HUMAN (14-171): 9.66e-65: 197: 94.30		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		666740 MYL9_HUMAN (14-171): 9.66e-65: 197: 94.30		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		534004 MLRV_HUMAN (9-165): 3e-55: 173: 58.23		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Mm
		906631 MLRV_MOUSE (9-165): 6.17e-55: 172: 56.96		MYH6_MOUSE (1-934): 0: 995: 25.97
+	Hs
		533985 MLRV_HUMAN (9-165): 3e-55: 173: 58.23		MYH1_HUMAN (12-802): 0: 980: 30.54
+	Hs
		169159 ML12B_HUMAN (13-171): 2.04e-65: 199: 99.37		MYO6_HUMAN (50-677): 1.7e-119: 397: 36.01