HitPredict

Interactor 1: NEBU (P20929)
Nebulin
Gene: NEB

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20936779
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 8525 Hs			1 2843
+	Hs
		635544 NEBU_HUMAN (1-8525): 0: 8654: 100.00		TITIN_HUMAN (731-2590): 1.4e-32: 142: 7.93
+	Hs
		274251 ITSN2_HUMAN (7807-8525): 4.4e-55: 217: 9.77		ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65
+	Hs
		1030639 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		ANK2_HUMAN (732-2368): 6.71e-37: 156: 10.07
+	Hs
		1417651 PACN1_HUMAN (8092-8525): 5.95e-65: 232: 15.91		TARA_HUMAN (1056-2768): 7.9e-31: 136: 8.16
+	Hs
		1431721 PACN3_HUMAN (8077-8525): 1.03e-57: 210: 11.84		TARA_HUMAN (1056-2768): 7.9e-31: 136: 8.16
+	Hs
		1431723 PACN2_HUMAN (8069-8525): 4e-54: 202: 13.94		TARA_HUMAN (1056-2768): 7.9e-31: 136: 8.16
+	Hs
		1117543 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		PCLO_HUMAN (2115-2843): 6.69e-19: 97.4: 7.82
+	Mm
		597663 SPTN1_MOUSE (7538-8525): 3.78e-57: 225: 10.74		ANK2_MOUSE (1984-2826): 8.33e-15: 83.7: 11.72
+	Hs
		571698 HCLS1_HUMAN (8096-8525): 3.27e-53: 199: 11.28		PCLO_HUMAN (2115-2843): 6.69e-19: 97.4: 7.82
+	Hs
		1117396 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		MICA3_HUMAN (2257-2836): 1.01e-09: 66.9: 17.77
+	Hs
		1117515 SPTN1_HUMAN (7876-8525): 2.02e-58: 229: 11.33		STAR9_HUMAN (1005-2819): 5.14e-09: 64.6: 8.69
+	Dm
		1302086 LASP1_DROME (7702-7839): 3.83e-09: 66.2: 20.86		TITIN_DROME (734-2294): 1.41e-38: 162: 9.18
+	Hs
		250282 VINEX_HUMAN (8153-8525): 1.65e-33: 143: 11.63		PHLB1_HUMAN (2052-2432): 6.94e-09: 64.1: 13.33