Interactor 1: TNR5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
Gene: CD40

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 32041822
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006954 - inflammatory response
GO:0019904 - protein domain specific binding
GO:0031625 - ubiquitin protein ligase binding
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 277
Hs

1 419
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Last updated: 15 Jul 2024