HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~fn3, PK_Tyr_Ser-Thr~SAM_1, SAM_1~SAM_1
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 1134
+	Hs
		710737 EPHA8_HUMAN (27-975): 0: 1031: 40.80		ANS1A_HUMAN (1-1134): 0: 772: 100.00
+	Hs
		710721 EPHA8_HUMAN (27-975): 0: 1031: 40.80		ANS1B_HUMAN (1-1101): 0: 565: 33.44
+	Hs
		710822 EPHB2_HUMAN (27-975): 0: 1109: 40.81		ANK3_HUMAN (3-989): 5.58e-84: 303: 15.12
+	Hs
		710868 EPHB2_HUMAN (27-975): 0: 1109: 40.81		CSKI2_HUMAN (1-592): 5.15e-68: 252: 24.96
+	Hs
		710207 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ANK3_HUMAN (3-989): 5.58e-84: 303: 15.12
+	Hs
		710562 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ANR50_HUMAN (65-988): 1.46e-76: 279: 13.82
+	Hs
		640288 EPHA1_HUMAN (1-976): 0: 1103: 100.00		TNKS2_HUMAN (3-188): 1.73e-45: 181: 30.65
+	Hs
		332386 EPHA1_HUMAN (1-976): 0: 1103: 100.00		TNKS1_HUMAN (2-237): 1.92e-44: 178: 23.26
+	Hs
		931913 EPHA5_HUMAN (3-975): 0: 1109: 41.71		KDIS_HUMAN (189-538): 2.35e-39: 161: 13.88
+	Hs
		710670 EPHA3_HUMAN (22-975): 0: 1100: 42.49		KDIS_HUMAN (189-538): 2.35e-39: 161: 13.88
+	Hs
		710348 EPHA2_HUMAN (24-976): 0: 1053: 49.90		MIB1_HUMAN (3-343): 1.55e-41: 168: 22.32
+	Hs
		710561 EPHA2_HUMAN (24-976): 0: 1053: 49.90		KDIS_HUMAN (189-538): 2.35e-39: 161: 13.88
+	Hs
		710812 EPHB2_HUMAN (27-975): 0: 1109: 40.81		ANK2_HUMAN (213-788): 7.76e-22: 105: 13.07
+	Hs
		640132 EPHA1_HUMAN (1-976): 0: 1103: 100.00		DAPK1_HUMAN (70-268): 8.81e-14: 78.6: 32.66
+	Hs
		720361 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		KDIS_HUMAN (189-538): 2.35e-39: 161: 13.88
+	Ce
		234056 SRC2_CAEEL (630-884): 6.42e-63: 223: 45.35		Q93203_CAEEL (4-1064): 1.57e-93: 327: 15.60
+	Hs
		1051020 FAK1_HUMAN (630-884): 1.18e-63: 236: 45.88		ANKH1_HUMAN (2-106): 2.09e-14: 80.6: 24.76