Interactor 1: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Interactor 2: SPT4 (P32914)
Transcription elongation factor SPT4 (Chromatin elongation factor SPT4)
Gene: SPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 19000817, 12556496, 12242279, 9450930, 16085932, 26945063, 16429126, 21386817, 16554755, 27376968, 29155810, 37968396, 23418395, 24859675
Identification Methods x-ray crystallography, anti tag coimmunoprecipitation, cosedimentation through density gradient, affinity chromatography technology, biochemical, pull down, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KOW~Spt4, Spt4~Spt5-NGN
Common GO terms GO:0000993 - RNA polymerase II complex binding
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0006368 - transcription elongation by RNA polymerase II
GO:0008298 - intracellular mRNA localization
and 8 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1063
Sc

1 102
+ Mm
+ Hs
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024