Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RFWD3 (Q6PCD5)
E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)
Gene: RFWD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 28575657, 28575658, 28666352, 30530694, 21558276, 21504906, 26474068, 29576527, 24126761, 24332808
Identification Methods affinity chromatography technology, enzymatic study, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016605 - PML body
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 616
Hs

1 774
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024