HitPredict

Interactor 1: Q8T8U1 (Q8T8U1)
Proteasome subunit beta
Gene: Prosbeta4R1

Interactor 2: PSA3 (Q9V5C6)
Proteasome subunit alpha type-3 (20S proteasome subunit alpha-7)
Gene: Prosalpha7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Dm			1 253
+	Sc
		636533 PSB4_YEAST (1-193): 2.36e-81: 242: 35.57		PSA7_YEAST (1-242): 7.28e-109: 317: 43.32
+	Sc
		636550 PSB5_YEAST (2-209): 2.45e-72: 222: 17.31		PSA7_YEAST (1-242): 7.28e-109: 317: 43.32
+	Dm
		1466091 PSB2_DROME (1-205): 5.5e-86: 254: 43.90		PSA3_DROME (1-253): 3.98e-96: 283: 100.00
+	Dm
		611545 PSB2_DROME (1-205): 5.5e-86: 254: 43.90		PSA4_DROME (4-240): 6.14e-96: 283: 26.94
+	Dm
		1376939 PSB2_DROME (1-205): 5.5e-86: 254: 43.90		PSA5_DROME (1-239): 2.65e-94: 278: 27.53
+	Hs
		681297 PSB2_HUMAN (1-197): 7.58e-82: 244: 33.50		PSA3_HUMAN (1-251): 1.92e-96: 284: 57.14
+	Hs
		887632 PSB2_HUMAN (1-197): 7.58e-82: 244: 33.50		PSA6_HUMAN (4-242): 6.62e-95: 280: 30.86
+	Hs
		165289 PSB2_HUMAN (1-197): 7.58e-82: 244: 33.50		PSA7_HUMAN (7-236): 1.5e-94: 279: 30.44
+	Hs
		700581 PSB2_HUMAN (1-197): 7.58e-82: 244: 33.50		PSA5_HUMAN (1-238): 3.7e-94: 278: 30.74
+	Hs
		681596 PSB2_HUMAN (1-197): 7.58e-82: 244: 33.50		PSA4_HUMAN (4-235): 6.08e-93: 275: 27.43
+	Sp
		1068357 PSB4_SCHPO (1-192): 1.76e-80: 240: 31.09		PSA3_SCHPO (4-242): 2.07e-93: 276: 31.43
+	Sc
		645140 PSB4_YEAST (1-193): 2.36e-81: 242: 35.57		PSA5_YEAST (1-251): 2.25e-91: 271: 27.69
+	Hs
		681258 PSB8_HUMAN (2-205): 2.9e-73: 224: 19.12		PSA3_HUMAN (1-251): 1.92e-96: 284: 57.14
+	Hs
		700448 PSB8_HUMAN (2-205): 2.9e-73: 224: 19.12		PSA6_HUMAN (4-242): 6.62e-95: 280: 30.86
+	Hs
		165265 PSB8_HUMAN (2-205): 2.9e-73: 224: 19.12		PSA7_HUMAN (7-236): 1.5e-94: 279: 30.44
+	Hs
		700432 PSB8_HUMAN (2-205): 2.9e-73: 224: 19.12		PSA5_HUMAN (1-238): 3.7e-94: 278: 30.74
+	Hs
		681574 PSB8_HUMAN (2-205): 2.9e-73: 224: 19.12		PSA4_HUMAN (4-235): 6.08e-93: 275: 27.43
+	Dm
		1484120 PSB2_DROME (1-205): 5.5e-86: 254: 43.90		PSA6_DROME (7-240): 5.43e-33: 122: 30.51
+	Sc
		645124 PSB4_YEAST (1-193): 2.36e-81: 242: 35.57		PSA3_YEAST (8-202): 2.59e-36: 130: 36.55
+	Sc
		661382 PSB5_YEAST (2-209): 2.45e-72: 222: 17.31		PSA3_YEAST (8-202): 2.59e-36: 130: 36.55