HitPredict

Interactor 1: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Interactor 2: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16477002
Identification Methods molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CRLF2-like_D2~CRLF2-like_D2, CRLF2-like_D2~TSLPR_D1
Common GO terms GO:0002335 - mature B cell differentiation
GO:0002361 - CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0002639 - positive regulation of immunoglobulin production
GO:0004896 - cytokine receptor activity
GO:0005654 - nucleoplasm
and 27 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 369
Hs

1 369
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Service provided by Combinatics, Japan

Last updated: 11Aug2025