HitPredict

Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: SSF1 (P38789)
Ribosome biogenesis protein SSF1
Gene: SSF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	11805826, 24312670, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 773 Sc			1 453
+	Sc
		415968 DED1_YEAST (146-611): 4.99e-117: 367: 25.31		SSF1_YEAST (1-453): 0: 544: 100.00
+	Sc
		699679 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		SSF1_YEAST (1-453): 0: 544: 100.00
+	Sc
		754899 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSF1_YEAST (1-453): 0: 544: 100.00
+	Sc
		699748 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		SSF2_YEAST (1-453): 0: 538: 94.04
+	Sc
		976889 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSF2_YEAST (1-453): 0: 538: 94.04
+	Hs
		1326334 DDX24_HUMAN (242-734): 2.14e-67: 241: 33.13		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33
+	Hs
		1292660 DDX27_HUMAN (57-587): 1.9e-39: 158: 28.55		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33
+	Hs
		1343143 DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33