Protein: RAD17
Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)

Gene: RAD17
Organism: Homo sapiens
Interactions: 93
UniProt ID: O75943

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000077 - DNA damage checkpoint signaling
GO:0003682 - chromatin binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

298620

RAD9A
Cell cycle checkpoint control protein RAD9A

9

6

Small-scale

0.974

High

298577

RFC4
Replication factor C subunit 4

6

20

Small-scale

0.948

High

298580

RFC5
Replication factor C subunit 5

6

20

Small-scale

0.948

High

298578

RFC2
Replication factor C subunit 2

5

20

Small-scale

0.931

High

261683

HUS1
Checkpoint protein HUS1

8

3

Small-scale

0.753

High

253181

RAD1
Cell cycle checkpoint protein RAD1

7

5

Small-scale

0.746

High

298597

ATR
Serine/threonine-protein kinase ATR

6

6

Small-scale

0.729

High

298581

RFC3
Replication factor C subunit 3

5

20

Small-scale

0.721

High

298583

PRS6B
26S proteasome regulatory subunit 6B

1

4

High-throughput

0.691

High

298596

ATM
Serine-protein kinase ATM

3

6

Small-scale

0.651

High

298579

RFC1
Replication factor C subunit 1

1

19

Small-scale

0.618

High

298604

RAD9B
Cell cycle checkpoint control protein RAD9B

1

6

Small-scale

0.618

High

298627

CLSPN
Claspin

2

0

Small-scale

0.598

High

298637

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

9

Small-scale

0.589

High

261984

NBN
Nibrin

1

1

Small-scale

0.569

High

298595

DPOE1
DNA polymerase epsilon catalytic subunit A

1

2

Small-scale

0.561

High

298613

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

Small-scale

0.561

High

298587

NH2L1
NHP2-like protein 1

1

2

Small-scale

0.552

High

74416

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.536

High

158385

RFXK
DNA-binding protein RFXANK

1

5

High-throughput

0.536

High

298561

CBX6
Chromobox protein homolog 6

1

3

High-throughput

0.536

High

298562

CBX7
Chromobox protein homolog 7

1

3

High-throughput

0.536

High

298566

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

298582

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.536

High

298593

PPARD
Peroxisome proliferator-activated receptor delta

1

4

High-throughput

0.536

High

298598

IKBB
NF-kappa-B inhibitor beta

1

2

High-throughput

0.536

High

298615

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

298619

TCPQM
T-complex protein 1 subunit theta-like 2

1

7

High-throughput

0.536

High

298621

NPAS1
Neuronal PAS domain-containing protein 1

1

6

High-throughput

0.536

High

298622

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.536

High

298623

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

298625

SENP3
Sentrin-specific protease 3

1

5

High-throughput

0.536

High

298631

H2AW
Core histone macro-H2A.2

1

12

High-throughput

0.536

High

298632

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.536

High

298635

TRI35
E3 ubiquitin-protein ligase TRIM35

1

1

High-throughput

0.536

High

298592

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.515

High

298128

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

298569

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

298600

EFMT2
EEF1A lysine methyltransferase 2

1

0

High-throughput

0.513

High

298602

SWAP1
ATPase SWSAP1

1

0

High-throughput

0.513

High

298608

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.513

High

298616

HES6
Transcription cofactor HES-6

1

0

High-throughput

0.513

High

298618

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

298626

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

298617

ANM6
Protein arginine N-methyltransferase 6

1

2

High-throughput

0.508

High

298584

KC1E
Casein kinase I isoform epsilon

1

1

Small-scale

0.501

High

298589

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.501

High

298590

CSK21
Casein kinase II subunit alpha

1

3

Small-scale

0.501

High

298585

MRE11
Double-strand break repair protein MRE11

1

1

Small-scale

0.500

High

298614

RAD50
DNA repair protein RAD50

1

7

Small-scale

0.500

High

238987

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

298563

LGI1
Leucine-rich glioma-inactivated protein 1

1

1

High-throughput

0.489

High

298609

SPART
Spartin

1

3

High-throughput

0.489

High

298610

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

298624

DNAI2
Dynein axonemal intermediate chain 2

1

5

High-throughput

0.489

High

298630

ASB6
Ankyrin repeat and SOCS box protein 6

1

2

High-throughput

0.489

High

219674

FOXO3
Forkhead box protein O3

1

2

Small-scale

0.479

High

240321

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

292953

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

298567

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

298571

RFA2
Replication protein A 32 kDa subunit

1

8

Small-scale

0.479

High

298572

H2AX
Histone H2AX

1

10

Small-scale

0.479

High

298574

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

Small-scale

0.479

High

298575

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.479

High

298576

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

298588

DPOE2
DNA polymerase epsilon subunit 2

1

1

Small-scale

0.479

High

298628

DPOE4
DNA polymerase epsilon subunit 4

1

1

Small-scale

0.479

High

298629

DPOE3
DNA polymerase epsilon subunit 3

1

2

Small-scale

0.479

High

298633

FZR1
Fizzy-related protein homolog

1

8

Small-scale

0.479

High

298634

ALK
ALK tyrosine kinase receptor

1

4

Small-scale

0.479

High

298565

LA
Lupus La protein

1

0

High-throughput

0.458

High

298594

CDK18
Cyclin-dependent kinase 18

1

0

Small-scale

0.458

High

298612

ATRIP
ATR-interacting protein

1

0

Small-scale

0.458

High

231542

PRKY
Putative serine/threonine-protein kinase PRKY

1

1

High-throughput

0.445

High

298591

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

Small-scale

0.408

High

298606

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

215468

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.279

Low

295557

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

296753

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

298564

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

298573

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

298586

RAB28
Ras-related protein Rab-28

1

0

High-throughput

0.279

Low

298599

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

298601

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.279

Low

298603

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

298605

DEFI8
Differentially expressed in FDCP 8 homolog

1

0

High-throughput

0.279

Low

298611

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.279

Low

298636

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.279

Low

298638

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

104976

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

298568

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

298570

CADH1
Cadherin-1

1

0

Small-scale

0.249

Low

298607

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025