HitPredict

Interactor 1: K1C20 (P35900)
Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT)
Gene: KRT20

Interactor 2: KRT84 (Q9NSB2)
Keratin, type II cuticular Hb4 (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)
Gene: KRT84

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 424 Hs			1 600
+	Hs
		475745 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C7_HUMAN (92-487): 1.26e-146: 433: 62.56
+	Hs
		436770 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C7_HUMAN (92-487): 1.26e-146: 433: 62.56
+	Hs
		437109 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C8_HUMAN (83-508): 1.98e-110: 341: 55.63
+	Hs
		436763 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C8_HUMAN (83-508): 1.98e-110: 341: 55.63
+	Hs
		341740 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C75_HUMAN (1-479): 7.03e-82: 269: 50.82
+	Hs
		566336 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C5_HUMAN (1-479): 3.8e-75: 252: 51.32
+	Hs
		777397 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C79_HUMAN (24-552): 4.6e-75: 250: 45.32
+	Hs
		407255 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C6B_HUMAN (1-479): 3.79e-73: 246: 52.98
+	Hs
		777381 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C6C_HUMAN (1-479): 8.82e-73: 245: 53.18
+	Hs
		777391 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C72_HUMAN (78-479): 1.05e-71: 241: 54.21
+	Hs
		385241 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C6A_HUMAN (1-479): 1.04e-70: 239: 52.98
+	Hs
		341723 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C75_HUMAN (1-479): 7.03e-82: 269: 50.82
+	Hs
		777388 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K22O_HUMAN (1-482): 5.4e-65: 226: 48.81
+	Hs
		436782 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C5_HUMAN (1-479): 3.8e-75: 252: 51.32
+	Hs
		551539 K1C20_HUMAN (1-424): 8.19e-156: 448: 100.00		K2C3_HUMAN (137-480): 1.79e-61: 216: 61.21
+	Hs
		407236 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C6B_HUMAN (1-479): 3.79e-73: 246: 52.98
+	Hs
		436822 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C6C_HUMAN (1-479): 8.82e-73: 245: 53.18
+	Hs
		385215 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C6A_HUMAN (1-479): 1.04e-70: 239: 52.98
+	Mm
		1424269 K1C17_MOUSE (27-418): 1.14e-143: 418: 50.25		K2C7_MOUSE (86-477): 1.41e-63: 218: 57.76
+	Hs
		436777 K1C18_HUMAN (1-415): 1.84e-141: 412: 44.03		K2C3_HUMAN (137-480): 1.79e-61: 216: 61.21