HitPredict

Interactor 1: K2C75 (O95678)
Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18)
Gene: KRT75

Interactor 2: K1C20 (P35900)
Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT)
Gene: KRT20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 32296183, 35575683, unassigned1304
Identification Methods two hybrid, cross-linking study, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045109 - intermediate filament organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 551
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025