HitPredict

Interactor 1: SCD2 (P40996)
Protein scd2/ral3
Gene: SCD2

Interactor 2: PPK2 (Q10447)
Protein kinase domain-containing protein ppk2
Gene: PPK2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23615447
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051286 - cell tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Sp			1 665
+	Sp
		830264 SCD2_SCHPO (1-536): 3.59e-168: 488: 100.00		STE20_SCHPO (44-655): 1.83e-133: 408: 19.52
+	Sc
		711524 BEM1_YEAST (2-492): 1.87e-83: 271: 29.28		STE20_YEAST (184-652): 8.79e-118: 375: 20.37
+	Hs
		221991 NCK2_HUMAN (4-269): 1.08e-35: 139: 14.18		PAK3_HUMAN (131-661): 4.85e-130: 396: 16.34
+	Hs
		297090 NCK1_HUMAN (3-232): 7.51e-35: 136: 15.97		PAK3_HUMAN (131-661): 4.85e-130: 396: 16.34
+	Hs
		222072 NCK2_HUMAN (4-269): 1.08e-35: 139: 14.18		PAK1_HUMAN (131-658): 2.9e-126: 386: 15.56
+	Hs
		593982 NCK1_HUMAN (3-232): 7.51e-35: 136: 15.97		PAK1_HUMAN (131-658): 2.9e-126: 386: 15.56
+	Ce
		1165105 Q95PW9_CAEEL (10-297): 3.2e-33: 132: 14.38		PK1_CAEEL (278-637): 1.08e-123: 380: 18.75
+	Mm
		312746 NCK1_MOUSE (3-232): 7.89e-35: 136: 15.97		PAK1_MOUSE (146-649): 3.91e-122: 375: 16.48
+	Hs
		222073 NCK2_HUMAN (4-269): 1.08e-35: 139: 14.18		PAK2_HUMAN (268-661): 3.17e-120: 370: 16.54
+	Hs
		593983 NCK1_HUMAN (3-232): 7.51e-35: 136: 15.97		PAK2_HUMAN (268-661): 3.17e-120: 370: 16.54
+	Hs
		1097207 SPD2A_HUMAN (302-470): 5.1e-29: 124: 21.74		PAK2_HUMAN (268-661): 3.17e-120: 370: 16.54
+	Dm
		1304979 NCK_DROME (31-297): 1.52e-27: 118: 16.84		PAK_DROME (281-657): 2.8e-119: 373: 18.59
+	Hs
		572819 NCF1_HUMAN (2-296): 6.72e-24: 105: 12.83		PAK1_HUMAN (131-658): 2.9e-126: 386: 15.56
+	Hs
		572784 NCF1_HUMAN (2-296): 6.72e-24: 105: 12.83		AKT1_HUMAN (345-664): 3.2e-126: 384: 15.77
+	Hs
		250214 VINEX_HUMAN (23-182): 4.8e-15: 80.3: 23.75		AKT2_HUMAN (343-656): 2.13e-130: 394: 15.08
+	Hs
		297104 ITSN1_HUMAN (8-92): 8.67e-12: 70.1: 22.99		PAK3_HUMAN (131-661): 4.85e-130: 396: 16.34
+	Hs
		250204 VINEX_HUMAN (23-182): 4.8e-15: 80.3: 23.75		KAPCA_HUMAN (349-658): 1.24e-127: 382: 16.46
+	Hs
		250242 VINEX_HUMAN (23-182): 4.8e-15: 80.3: 23.75		PAK2_HUMAN (268-661): 3.17e-120: 370: 16.54
+	Hs
		250355 VINEX_HUMAN (23-182): 4.8e-15: 80.3: 23.75		PAK5_HUMAN (355-636): 6.7e-115: 362: 21.68
+	Sc
		711541 BEM1_YEAST (2-492): 1.87e-83: 271: 29.28		SKM1_YEAST (412-637): 1.42e-11: 69.7: 24.79