HitPredict

Interactor 1: PERI (P41219)
Peripherin (Neurofilament 4)
Gene: PRPH

Interactor 2: K1C12 (Q99456)
Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12)
Gene: KRT12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005198 - structural molecule activity GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 470 Hs			1 494
+	Hs
		833254 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C17_HUMAN (119-491): 6.03e-150: 436: 60.05
+	Hs
		385062 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C14_HUMAN (94-490): 1.31e-147: 432: 58.44
+	Hs
		566110 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C10_HUMAN (120-434): 4.88e-129: 388: 69.21
+	Hs
		385038 VIME_HUMAN (10-458): 3.82e-146: 427: 56.79		K1C14_HUMAN (94-490): 1.31e-147: 432: 58.44
+	Hs
		475537 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C19_HUMAN (112-436): 8.6e-128: 379: 65.23
+	Hs
		618006 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C15_HUMAN (124-490): 4.65e-126: 376: 58.86
+	Hs
		476277 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C16_HUMAN (121-436): 5.51e-125: 374: 67.09
+	Hs
		833304 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C27_HUMAN (44-493): 9.76e-113: 342: 51.77
+	Hs
		833275 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1H1_HUMAN (119-436): 3.63e-109: 332: 54.40
+	Hs
		777379 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K1C20_HUMAN (118-492): 1.26e-107: 328: 50.13
+	Hs
		833374 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		KRT84_HUMAN (20-463): 1.75e-102: 321: 26.29
+	Hs
		341747 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C75_HUMAN (8-443): 3.65e-89: 284: 24.73
+	Hs
		833283 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C71_HUMAN (17-443): 1.2e-84: 272: 22.94
+	Hs
		833269 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C72_HUMAN (7-443): 1.52e-83: 269: 23.20
+	Hs
		407258 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C6B_HUMAN (91-443): 9.04e-76: 250: 26.27
+	Hs
		566339 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C5_HUMAN (91-443): 1.2e-75: 250: 27.40
+	Hs
		833237 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C6C_HUMAN (91-443): 1.27e-75: 249: 26.84
+	Hs
		385245 PERI_HUMAN (1-470): 3.75e-165: 475: 100.00		K2C6A_HUMAN (91-443): 1.43e-74: 247: 26.84
+	Hs
		341725 VIME_HUMAN (10-458): 3.82e-146: 427: 56.79		K2C75_HUMAN (8-443): 3.65e-89: 284: 24.73
+	Hs
		385219 VIME_HUMAN (10-458): 3.82e-146: 427: 56.79		K2C6A_HUMAN (91-443): 1.43e-74: 247: 26.84