HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: RMXL1 (Q96E39)
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1)
Gene: RBMXL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 499 Hs			1 390
+	Hs
		745096 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		RBMX_HUMAN (1-390): 4.19e-44: 158: 92.07
+	Hs
		745097 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBMX_HUMAN (1-390): 4.19e-44: 158: 92.07
+	Hs
		834097 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RMXL1_HUMAN (1-357): 3.75e-42: 153: 100.00
+	Hs
		833998 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		RBM7_HUMAN (2-268): 6.54e-33: 126: 22.68
+	Hs
		833740 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		SAFB1_HUMAN (7-390): 4.69e-33: 133: 14.25
+	Hs
		483432 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBY1A_HUMAN (1-363): 4.07e-32: 128: 48.53
+	Hs
		834049 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBY1F_HUMAN (1-363): 7.89e-32: 127: 48.27
+	Hs
		833874 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		625657 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		RBM7_HUMAN (2-268): 6.54e-33: 126: 22.68
+	Hs
		834030 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		833880 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		833736 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		834033 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		PABP4_HUMAN (8-97): 3.48e-19: 91.5: 28.89
+	Hs
		625400 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		ELAV2_HUMAN (2-133): 2.03e-23: 101: 24.09
+	Hs
		745160 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		RBMX_HUMAN (1-390): 4.19e-44: 158: 92.07
+	Hs
		834041 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBM39_HUMAN (3-112): 6.61e-15: 77.9: 22.73
+	Hs
		267583 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		RMXL2_HUMAN (1-390): 1.45e-32: 128: 66.16
+	Hs
		414930 CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95		SAFB1_HUMAN (7-390): 4.69e-33: 133: 14.25
+	Hs
		267560 CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95		RMXL2_HUMAN (1-390): 1.45e-32: 128: 66.16
+	Hs
		625359 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		RBM3_HUMAN (8-88): 1.05e-15: 75.9: 55.56