HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Tropomyosin
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 248
+	Hs
		447700 ACTY_HUMAN (1-376): 0: 776: 100.00		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		482870 ACTZ_HUMAN (1-376): 0: 728: 90.43		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Hs
		447728 ACTZ_HUMAN (1-376): 0: 728: 90.43		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		958413 ACTZ_HUMAN (1-376): 0: 728: 90.43		TPM4_HUMAN (1-248): 5.58e-47: 158: 100.00
+	Hs
		464138 ACTZ_HUMAN (1-376): 0: 728: 90.43		TPM2_HUMAN (4-248): 5.06e-42: 146: 69.39
+	Hs
		482879 ACTG_HUMAN (7-376): 0: 579: 53.74		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Hs
		482868 ACTB_HUMAN (8-376): 0: 578: 53.62		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Mm
		953255 ACTB_MOUSE (8-376): 0: 578: 53.62		TPM4_MOUSE (1-248): 1.79e-48: 162: 95.97
+	Dm
		387020 ACT4_DROME (8-376): 0: 604: 53.35		TPM2_DROME (5-246): 7.27e-38: 135: 42.98
+	Hs
		482881 ACTC_HUMAN (5-376): 0: 576: 53.72		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Hs
		447734 ACTG_HUMAN (7-376): 0: 579: 53.74		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		482876 ACTA_HUMAN (5-376): 0: 575: 53.46		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Mm
		946685 ACTA_MOUSE (5-376): 0: 575: 53.46		TPM1_MOUSE (4-248): 1.11e-48: 163: 68.57
+	Hs
		447727 ACTB_HUMAN (8-376): 0: 578: 53.62		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Oc
		946702 ACTS_RABIT (5-376): 0: 574: 53.19		TPM1_RABIT (4-248): 1.11e-48: 163: 68.57
+	Hs
		952730 ACTB_HUMAN (8-376): 0: 578: 53.62		TPM4_HUMAN (1-248): 5.58e-47: 158: 100.00
+	Hs
		464137 ACTB_HUMAN (8-376): 0: 578: 53.62		TPM2_HUMAN (4-248): 5.06e-42: 146: 69.39
+	Rn
		97300 ACTB_RAT (8-376): 0: 578: 53.62		CTRO_RAT (4-247): 4.49e-39: 146: 20.24
+	Ce
		534407 ACT4_CAEEL (8-376): 0: 578: 54.42		TPM1_CAEEL (4-246): 2.56e-38: 136: 51.03
+	Dm
		482721 ACT5_DROME (8-376): 0: 575: 53.89		TPM2_DROME (5-246): 7.27e-38: 135: 42.98