HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: KLDC3 (Q9BQ90)
Kelch domain-containing protein 3 (Testis intracellular mediator protein)
Gene: KLHDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 382
+	Sc
		585343 MYO2_YEAST (162-947): 2.18e-95: 343: 12.05		KEL2_YEAST (109-331): 3.12e-32: 130: 21.25
+	Hs
		1271023 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		KLDC3_HUMAN (1-382): 2.75e-117: 347: 100.00
+	Hs
		1049211 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		KEAP1_HUMAN (85-381): 2.76e-68: 228: 13.71
+	Sc
		585311 MYO2_YEAST (162-947): 2.18e-95: 343: 12.05		KEL1_YEAST (226-335): 4.91e-11: 66.6: 22.22
+	Hs
		1066810 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		KLHL9_HUMAN (1-188): 2.78e-31: 127: 14.58
+	Hs
		231769 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		KLH20_HUMAN (2-189): 1.45e-36: 142: 18.62
+	Hs
		1049213 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		KEAP1_HUMAN (85-381): 2.76e-68: 228: 13.71
+	Hs
		1050084 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		KLH13_HUMAN (140-381): 1.58e-39: 150: 15.39
+	Dm
		113322 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		LZTR1_DROME (2-215): 5.45e-37: 144: 17.86
+	Hs
		1050083 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		KLHL9_HUMAN (1-188): 2.78e-31: 127: 14.58