Interactor 1: PAXI (P49023)
Paxillin
Gene: PXN
Interactor 2: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 1.00 | 0.935 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16628223, 11251077, 31980649, 34079125, unassigned2173, 22728435 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~LIM, GIT1_C~Paxillin |
| Common GO terms | GO:0005925 - focal adhesion |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
